Intermediates

2-Fluoro-5-nitrobenzoic acid

  • CAS No.7304-32-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoro-5-nitrobenzoic acid (CAS 7304-32-7) designed for advanced organic synthesis. Reliable supply with ≥99.0% HPLC purity for pharmaceutical intermediates.

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Product Technical Details

Product Overview

2-Fluoro-5-nitrobenzoic acid is a specialized fluorinated aromatic compound serving as a critical building block in modern medicinal chemistry and agrochemical development. As a key intermediate, this substance enables the introduction of both fluoro and nitro functional groups into complex molecular architectures, facilitating the synthesis of high-value pharmaceutical active ingredients. Our manufacturing process ensures consistent quality, making it an ideal choice for research laboratories and large-scale production facilities requiring reliable raw materials.

The strategic placement of the fluorine atom at the ortho position relative to the carboxylic acid group enhances the reactivity of the molecule towards nucleophilic aromatic substitution. This characteristic is particularly valuable in the construction of heterocyclic systems found in numerous therapeutic agents. By sourcing this material from a dedicated global manufacturer, clients gain access to a supply chain optimized for stability, purity, and regulatory compliance.

Key Specifications

ParameterSpecification
Chemical Name2-Fluoro-5-nitrobenzoic acid
CAS Number7304-32-7
Molecular FormulaC7H4FNO4
Molecular Weight185.11 g/mol
AppearancePeachy beige crystals
Purity (HPLC)≥99.0%
Melting Point142-144°C
Density1.568 g/cm³
Flash Point158°C

Industrial Applications

This fluorinated benzoic acid derivative is extensively utilized in the preparation of diverse organic compounds. Its primary role involves serving as a precursor in multi-step synthesis routes where specific substitution patterns are required. The high purity grade provided ensures minimal side reactions during downstream processing, thereby improving overall yield and reducing purification costs.

  • Pharmaceutical Intermediate: Essential for synthesizing quinolone antibiotics and other fluorinated drug candidates.
  • Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides requiring specific electronic properties.
  • Material Science: Applicable in the creation of specialized polymers and liquid crystal materials.
  • Research and Development: A standard reagent for academic and industrial labs focusing on organic methodology.

Quality Assurance and Storage

Every batch of 2-Fluoro-5-nitrobenzoic acid undergoes rigorous quality control testing, including high-performance liquid chromatography (HPLC) analysis to verify purity levels. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure full traceability and compliance with international standards. Proper handling is essential to maintain product integrity over time.

For optimal preservation, the material should be stored in a cool, well-ventilated area away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, which are designed to protect the contents during transit. Custom packaging solutions are available upon request to meet specific logistical requirements. Our commitment to safety and quality makes us a preferred partner for businesses seeking dependable chemical supplies.