2-Fluoro-5-(trifluoromethoxy)benzoic acid
- CAS No.886497-85-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity fluorinated building block for pharmaceutical and agrochemical synthesis. Reliable supply with COA.
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Product Overview
2-Fluoro-5-(trifluoromethoxy)benzoic acid is a specialized fluorinated aromatic intermediate designed for advanced organic synthesis applications. This compound features a unique substitution pattern combining a fluorine atom and a trifluoromethoxy group on the benzene ring, offering distinct electronic and steric properties valuable in medicinal chemistry and material science. As a key building block, it facilitates the introduction of fluorinated moieties into complex molecular structures, enhancing metabolic stability and lipophilicity in final products.
Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial scale-up. We adhere to strict quality control protocols to guarantee that every batch meets the specified chemical standards. This product serves as a reliable precursor for developing novel pharmaceutical agents, agrochemical formulations, and functional materials where fluorine chemistry plays a critical role.
Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Fluoro-5-(trifluoromethoxy)benzoic acid |
| CAS Number | 886497-85-4 |
| Molecular Formula | C8H4F4O3 |
| Molecular Weight | 224.11 g/mol |
| Purity (Assay) | ≥98.0% |
| Density | 1.529 g/cm3 |
| Boiling Point | 251.9 °C |
| Flash Point | 106.1 °C |
| Refractive Index | 1.462 |
Industrial Applications
This fluorinated benzoic acid derivative is primarily utilized as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). The presence of the trifluoromethoxy group often improves the bioavailability and binding affinity of drug candidates. Additionally, it finds application in agrochemical development, where fluorinated structures contribute to enhanced pesticidal activity and environmental stability. Material scientists also employ this compound in the creation of polymers and liquid crystals with specific thermal and optical properties.
- Medicinal chemistry building block for kinase inhibitors
- Precursor for agrochemical active ingredients
- Component in advanced organic material synthesis
- Research reagent for fluorination studies
Quality Assurance and Handling
We prioritize product integrity through comprehensive quality assurance measures. Each shipment is accompanied by a Certificate of Analysis (COA) verifying purity and physical constants. Our facility maintains optimal storage conditions to prevent degradation, ensuring the chemical remains stable until it reaches your laboratory. Packaging is designed to protect the contents from moisture and physical damage during international transit.
For storage, keep the container tightly closed in a cool, ventilated place away from incompatible substances. Standard safety precautions for handling organic acids should be observed, including the use of appropriate personal protective equipment. We offer flexible packaging options, including 25 kg drums, and can accommodate custom requirements based on project volume. Contact our sales team for bulk pricing and technical support regarding synthesis routes.
