2-Fluoro-5-(trifluoromethyl)pyridine
- CAS No.69045-82-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-5-(trifluoromethyl)pyridine (CAS 69045-82-5), a key fluorinated heterocyclic intermediate for advanced pharmaceutical synthesis.
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Product Overview
2-Fluoro-5-(trifluoromethyl)pyridine is a high-value fluorinated heterocyclic compound widely employed as a critical building block in the development of complex pharmaceutical active ingredients. With its unique combination of electron-withdrawing trifluoromethyl and fluorine substituents on the pyridine ring, this molecule offers enhanced metabolic stability, lipophilicity, and binding affinity—properties highly sought after in modern medicinal chemistry. Our product is manufactured under stringent quality control protocols to ensure consistent performance in demanding synthetic applications.
Specifications
| Molecular Formula | C6H3F4N |
|---|---|
| Molecular Weight | 165.09 g/mol |
| CAS Number | 69045-82-5 |
| Appearance | Colorless liquid |
| Purity | ≥98.0% |
| Density | 1.371 g/cm³ |
| Boiling Point | 135.3°C at 760 mmHg |
| Flash Point | 35.6°C |
| Refractive Index | 1.402 |
Industrial Applications
This compound serves primarily as a specialty intermediate in the synthesis of advanced organic molecules targeting neurological therapeutics and other regulated pharmaceutical pathways. Its structural features enable efficient derivatization via cross-coupling, nucleophilic substitution, and metal-halogen exchange reactions. Key application areas include:
- Construction of fluorinated pyridine cores in drug discovery programs
- Synthesis of agrochemical actives requiring enhanced environmental persistence
- Development of novel ligands for catalytic systems in fine chemical production
Stored in tightly sealed containers under cool, dry conditions, 2-Fluoro-5-(trifluoromethyl)pyridine maintains stability during transport and long-term warehousing. Supplied in 250 kg drums for industrial-scale operations, it meets global regulatory standards for B2B chemical distribution.
