2-Fluoro-6-methylaniline
- CAS No.443-89-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-6-methylaniline (CAS 443-89-0) is a vital fluorinated building block designed for complex organic synthesis and pharmaceutical intermediate production.
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Product Overview
2-Fluoro-6-methylaniline stands as a premier choice for chemists engaged in the development of sophisticated organic molecules. As a fluorinated aromatic amine, this compound offers unique reactivity profiles that are essential for modern synthetic pathways. Our production facility is dedicated to supplying this key intermediate with consistent quality, ensuring that downstream processes proceed without interruption. The strategic placement of the fluorine atom ortho to the amino group, combined with the methyl substituent, creates a steric environment that influences reaction kinetics and selectivity. This makes it an invaluable asset for constructing complex molecular architectures required in various industrial sectors.
In the realm of pharmaceutical research, fluorinated building blocks are increasingly demanded to enhance the metabolic stability of drug candidates. This specific aniline derivative serves as a versatile precursor for numerous coupling reactions, including palladium-catalyzed cross-couplings and nucleophilic aromatic substitutions. By incorporating this intermediate, researchers can introduce specific electronic effects that improve the binding affinity and pharmacokinetic properties of final products. We understand the critical nature of supply chain reliability in drug development timelines. Therefore, our manufacturing protocols are designed to maintain high purity levels, minimizing the presence of isomeric impurities that could complicate purification steps later in the synthesis sequence.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 443-89-0 |
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Appearance | Light yellow transparent liquid |
| Purity | ≥98.0% |
| Density | 1.082 g/mL at 25°C |
| Refractive Index | n20/D 1.536 |
| Water Content | ≤0.5% |
Industrial Applications
Beyond life sciences, this chemical exhibits significant utility in the agrochemical and materials science industries. It acts as a fundamental component in the synthesis of specialized polymers and crop protection agents. The stability of the carbon-fluorine bond contributes to the durability and performance of end-use materials. Our team works closely with clients to understand their specific formulation requirements, offering technical support to optimize integration into existing production lines. We provide comprehensive documentation, including certificates of analysis, to facilitate regulatory compliance and quality audits.
- Versatile precursor for pharmaceutical intermediate synthesis.
- Essential building block for agrochemical development.
- Used in creating specialized fluorinated polymeric materials.
- Supports diverse coupling and substitution reaction pathways.
Quality Control and Safety
Safety and handling are paramount in our operations. Classified as a flammable liquid, this product requires adherence to strict storage guidelines to prevent hazards. We recommend keeping containers tightly closed in cool, well-ventilated areas away from ignition sources. Our packaging solutions utilize robust drums designed to withstand international shipping conditions, ensuring the product arrives in optimal condition. Each batch undergoes rigorous testing using advanced chromatographic and spectroscopic methods. This commitment to quality assurance guarantees that every shipment meets the specified parameters for purity and physical properties. Partnering with us means accessing a reliable source of high-performance chemical intermediates backed by decades of industry expertise.
