2-Fluoro-6-methylnicotinonitrile
- CAS No.54957-80-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-6-methylnicotinonitrile (CAS 54957-80-1) designed for advanced pharmaceutical intermediate synthesis and organic chemistry applications.
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Product Overview
2-Fluoro-6-methylnicotinonitrile is a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. Identified by the unique CAS registry number 54957-80-1, this chemical entity features a pyridine ring substituted with both fluorine and methyl groups, alongside a nitrile functionality. This specific arrangement of functional groups provides unique reactivity profiles, making it an invaluable precursor for the development of complex pharmaceutical agents and agrochemical formulations.
Our manufacturing process ensures that every batch meets rigorous international quality standards. The presence of the fluorine atom at the 2-position enhances metabolic stability and lipophilicity in downstream drug candidates, which is a key consideration in contemporary drug design. As a trusted global manufacturer, we prioritize consistency and reliability, supplying research institutions and industrial partners with materials that facilitate efficient synthesis routes.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Fluoro-6-methylnicotinonitrile |
| CAS Number | 54957-80-1 |
| Molecular Formula | C7H5FN2 |
| Molecular Weight | 136.13 g/mol |
| Appearance | White Crystalline Powder |
| Purity | ≥98.0% |
| Boiling Point | 235.3±35.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Refractive Index | 1.506 |
Industrial Applications
This compound is primarily utilized as a pharmaceutical intermediate in the synthesis of bioactive molecules. The nitrile group offers a versatile handle for further chemical transformations, such as hydrolysis to carboxylic acids or reduction to amines, enabling diverse synthetic pathways. Fluorinated pyridines are increasingly sought after in the development of kinase inhibitors and other therapeutic classes where enhanced binding affinity and pharmacokinetic properties are required.
Beyond pharmaceuticals, this chemical finds utility in the creation of advanced materials and specialty chemicals. Researchers value its stability and reactivity balance for constructing complex molecular architectures. Whether used in scale-up production or early-stage discovery, our material supports high-yield reactions and minimizes impurity profiles, ensuring smoother downstream processing.
Quality Assurance and Safety
We maintain a comprehensive quality management system to guarantee product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing test results against specified parameters. Our facilities adhere to strict safety protocols during production and handling to mitigate any potential risks associated with chemical manufacturing.
- Consistent batch-to-batch reproducibility
- Advanced analytical testing using HPLC and NMR
- Compliance with international shipping regulations
- Dedicated technical support for application guidance
Storage and Handling
To maintain optimal quality, 2-Fluoro-6-methylnicotinonitrile should be stored in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation. Standard laboratory safety practices, including the use of personal protective equipment (PPE), should be observed during handling to ensure personnel safety. For bulk orders, we offer secure packaging in 25 kg drums, ensuring the product arrives in pristine condition ready for immediate use in your synthesis workflows.
