2-Fluoro-6-nitrobenzoic acid
- CAS No.385-02-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-6-nitrobenzoic acid (CAS 385-02-4) designed for advanced organic synthesis. Reliable supply with ≥99.0% purity for pharmaceutical and chemical manufacturing.
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Product Overview
2-Fluoro-6-nitrobenzoic acid is a highly specialized fluorinated aromatic compound that serves as a vital building block in modern organic synthesis. Characterized by the presence of both fluoro and nitro functional groups on the benzene ring, this chemical intermediate offers unique reactivity profiles essential for constructing complex molecular architectures. Our facility produces this compound under stringent quality control protocols to ensure consistency across batches, making it an ideal choice for research and industrial-scale applications.
The strategic positioning of the fluorine atom at the ortho position relative to the carboxylic acid group enhances the compound's electrophilic properties, facilitating various nucleophilic aromatic substitution reactions. This makes it particularly valuable in the development of pharmaceuticals, agrochemicals, and advanced materials where fluorine incorporation is critical for improving metabolic stability and bioavailability.
Key Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Fluoro-6-nitrobenzoic acid |
| CAS Number | 385-02-4 |
| Molecular Formula | C7H4FNO4 |
| Molecular Weight | 185.11 g/mol |
| Appearance | Peach tan powder |
| Purity (HPLC) | ≥99.0% |
| Density | 1.568 g/cm3 |
| Boiling Point | 344.2°C |
| Flash Point | 162°C |
Industrial Applications
As a versatile intermediate, 2-Fluoro-6-nitrobenzoic acid finds extensive use in the synthesis of heterocyclic compounds and substituted anilines. The nitro group can be readily reduced to an amine, opening pathways to create diverse derivatives used in drug discovery pipelines. Additionally, the carboxylic acid functionality allows for amidation or esterification, providing chemists with multiple handles for further functionalization.
In the agrochemical sector, this compound serves as a precursor for herbicides and fungicides that require specific fluorinated motifs to enhance environmental stability. Material science researchers also utilize this building block to develop polymers with improved thermal and chemical resistance properties. Our global manufacturing network ensures that clients receive materials that meet the rigorous demands of these high-value industries.
Quality Assurance and Safety
We prioritize product integrity through comprehensive testing procedures. Each batch undergoes analysis via High-Performance Liquid Chromatography (HPLC) to verify purity levels exceeding 99.0%. Certificates of Analysis (COA) are provided with every shipment to document compliance with specified parameters. Our production processes adhere to international safety standards, minimizing impurities and ensuring reliable performance in downstream reactions.
Regarding handling, this substance should be managed with appropriate personal protective equipment. It is classified as a chemical intermediate and should be used in well-ventilated environments to prevent inhalation of dust. Proper storage conditions are essential to maintain product stability over time.
Packaging and Storage
To preserve quality during transit, 2-Fluoro-6-nitrobenzoic acid is packaged in durable 25 kg drums lined with protective materials. Custom packaging solutions are available upon request to accommodate specific logistical requirements. The product should be stored in a cool, dry, and ventilated area away from direct sunlight and incompatible substances. Following these guidelines ensures the chemical remains stable and ready for use upon arrival at your facility.
