2-Fluoro-6-nitrotoluene
- CAS No.769-10-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoro-6-nitrotoluene (CAS 769-10-8) designed for pharmaceutical and agrochemical synthesis. Available in bulk quantities with strict quality control.
Request Bulk PricingProduct Technical Details
Product Overview
2-Fluoro-6-nitrotoluene is a specialized fluorinated aromatic compound serving as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern, this chemical intermediate enables the construction of complex molecular architectures required in advanced pharmaceutical and agrochemical development. Our manufacturing process ensures high consistency and reliability for downstream applications, meeting the rigorous demands of global chemical supply chains.
As a key member of the fluorinated nitrobenzene family, this compound offers superior reactivity profiles suitable for nucleophilic aromatic substitution and reduction reactions. The presence of the fluorine atom enhances metabolic stability and lipophilicity in final drug candidates, making it a preferred choice for medicinal chemists designing next-generation therapeutics. We prioritize safety and quality in every batch produced.
Chemical Properties and Reactivity
This versatile intermediate exhibits distinct physical and chemical properties that facilitate its use in various synthetic pathways. The nitro group provides a handle for reduction to aniline derivatives, while the fluorine substituent allows for specific nucleophilic displacement reactions. These characteristics make it invaluable for creating diverse chemical libraries and optimizing lead compounds in drug discovery programs.
The stability of the aromatic ring combined with the electron-withdrawing nature of the nitro group ensures predictable reaction outcomes. Our production facilities utilize advanced catalytic processes to minimize impurities, ensuring that the final product meets or exceeds industry standards for purity and performance.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 769-10-8 |
| Molecular Formula | C7H6FNO2 |
| Molecular Weight | 155.13 g/mol |
| Appearance | Colorless to light yellow transparent liquid |
| Purity | ≥98.0% |
| Water Content | ≤0.5% |
| Density | 1.27 g/mL at 25 °C |
| Boiling Point | 97 °C at 11 mm Hg |
| Melting Point | 6.5-7 °C |
| Refractive Index | n20/D 1.523 |
| Flash Point | 192 °F |
Industrial Applications
This versatile intermediate is extensively utilized across multiple high-value sectors. In the pharmaceutical industry, it serves as a precursor for synthesizing active pharmaceutical ingredients (APIs) targeting various therapeutic areas. The fluorine moiety is particularly valuable for optimizing pharmacokinetic properties and binding affinity in biological systems.
- Pharmaceutical Synthesis: Used in the production of complex drug molecules requiring fluorinated aromatic cores for enhanced efficacy.
- Agrochemical Development: Essential for creating novel crop protection agents with enhanced environmental stability and pest resistance.
- Organic Research: Employed in laboratory settings for developing new synthetic methodologies and reaction pathways in academic and industrial labs.
- Material Science: Occasionally utilized in the synthesis of specialized polymers and functional materials requiring specific electronic properties.
Quality Assurance and Safety
We adhere to strict quality management systems to guarantee product integrity. Every batch undergoes rigorous testing using advanced analytical techniques such as Gas Chromatography (GC), High-Performance Liquid Chromatography (HPLC), and Nuclear Magnetic Resonance (NMR) to confirm identity and purity. A Certificate of Analysis (COA) is provided with each shipment to ensure compliance with your specific requirements and regulatory standards.
Regarding safety, this material should be handled in a well-ventilated environment using appropriate personal protective equipment including gloves and eye protection. Storage conditions require a cool, dry place away from incompatible substances such as strong oxidizing agents. Our packaging solutions, typically 25kg drums made of plastic or plastic-coated iron, are designed to maintain stability during global transit and prevent contamination.
Our commitment to excellence extends beyond product quality to include reliable logistics and customer support. We offer flexible packaging options and can accommodate custom synthesis requests for specific purity grades or derivative compounds. Partner with us for a secure supply of high-performance chemical intermediates.
