2-Fluoroadenine
- CAS No.700-49-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoroadenine (CAS 700-49-2) designed for pharmaceutical synthesis, offering exceptional stability and purity for API manufacturing.
Request Bulk PricingProduct Technical Details
Product Overview
2-Fluoroadenine is a specialized fluorinated purine derivative that serves as a critical building block in the synthesis of advanced nucleoside analogues. As a key pharmaceutical intermediate, this compound is extensively utilized in the development of therapeutic agents, particularly within the oncology sector. Our manufacturing process ensures that every batch meets rigorous international standards for chemical purity and structural integrity. The introduction of a fluorine atom at the second position of the adenine ring significantly enhances the metabolic stability and biological activity of downstream products, making it an indispensable component for modern medicinal chemistry.
We understand the demanding requirements of pharmaceutical research and production. Therefore, our facility employs state-of-the-art synthetic methodologies to produce 2-Fluoroadenine with consistent quality. This compound is characterized by its high thermal stability and specific reactivity profile, which facilitates efficient coupling reactions in multi-step synthesis pathways. Whether used for laboratory-scale research or large-scale commercial production, our material provides a reliable foundation for creating high-value active pharmaceutical ingredients.
Key Specifications
Quality control is paramount in the production of pharmaceutical intermediates. We utilize high-performance liquid chromatography (HPLC) and other advanced analytical techniques to verify the composition of each lot. The following table outlines the standard technical specifications for our commercial grade 2-Fluoroadenine:
| Parameter | Specification |
|---|---|
| Appearance | Off-white to White Powder |
| CAS Number | 700-49-2 |
| Molecular Formula | C5H4FN5 |
| Molecular Weight | 153.12 g/mol |
| Assay (HPLC) | ≥98.0% |
| Loss on Drying | ≤2.0% |
| Related Substances | Complies with Standard |
Industrial Applications
The primary application of 2-Fluoroadenine lies in the synthesis of nucleoside analogues used in chemotherapy and antiviral treatments. It acts as a precursor for compounds such as Fludarabine, which is vital for treating hematological malignancies. The high purity level of our intermediate minimizes the formation of unwanted by-products during subsequent reaction steps, thereby improving overall yield and reducing purification costs for our clients. Additionally, this chemical is valuable in organic synthesis research where fluorinated heterocycles are required for structure-activity relationship studies.
Quality Assurance and Safety
Our commitment to excellence extends beyond mere compliance. We implement a comprehensive quality management system that tracks every stage of production from raw material sourcing to final packaging. Each shipment is accompanied by a detailed Certificate of Analysis (COA) that verifies all critical quality attributes. To maintain product stability, we recommend specific storage conditions that protect the material from moisture and excessive heat.
- Strict impurity profiling to ensure safety
- Batch-to-batch consistency for reliable processing
- Secure packaging to prevent contamination
- Global logistics support for timely delivery
Storage and Handling
To preserve the chemical integrity of 2-Fluoroadenine, it should be stored in a cool, dry, and well-ventilated area away from direct sunlight. Containers must be kept tightly closed when not in use to prevent absorption of moisture from the atmosphere. Proper handling procedures, including the use of personal protective equipment, should be followed during transfer and weighing operations to ensure personnel safety and product purity.
