2-Fluoroadenosine
- CAS No.146-78-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoroadenosine (CAS 146-78-1) designed for pharmaceutical synthesis. Reliable supply with strict quality control and comprehensive documentation.
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Product Overview
2-Fluoroadenosine represents a critical specialized building block within the modern pharmaceutical industry, specifically serving as a key precursor in the synthesis of advanced nucleoside analogs. Our facility specializes in the production of this high-value chemical intermediate, ensuring that every batch meets rigorous international standards for purity and consistency. As a fluorinated purine derivative, this compound plays an indispensable role in the development of therapeutic agents, particularly within the oncology sector where precision chemistry is paramount.
We understand that reliability in the supply chain is just as important as chemical quality. Therefore, our manufacturing protocols are designed to support large-scale production needs while maintaining the flexibility to accommodate custom research requirements. This product is strictly intended for industrial pharmaceutical synthesis and laboratory research purposes, adhering to all relevant safety and compliance regulations for chemical intermediates.
Chemical Properties and Specifications
The structural integrity of 2-Fluoroadenosine is defined by its specific molecular configuration, which includes a fluorine substitution at the second position of the purine ring. This modification significantly influences the chemical reactivity and stability of the molecule, making it an ideal candidate for subsequent synthetic transformations. Our quality control team utilizes advanced analytical techniques, including high-performance liquid chromatography (HPLC), to verify the identity and purity of each lot before release.
| Parameter | Specification |
|---|---|
| CAS Number | 146-78-1 |
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.23 g/mol |
| Appearance | White or almost white crystalline powder |
| Purity (HPLC) | ≥98.0% |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤20 ppm |
| Residue on Ignition | ≤0.05% |
| Total Impurities | ≤1.5% |
Industrial Applications
The primary application of this intermediate lies in the manufacturing of complex pharmaceutical active ingredients. It serves as a vital starting material for the synthesis of Fludarabine and its phosphate derivatives, which are well-known components in chemotherapy regimens. The high purity level of our 2-Fluoroadenosine ensures that downstream reactions proceed with optimal yield and minimal byproduct formation, thereby reducing overall production costs for our partners.
Beyond its role in oncology drug synthesis, this compound is also utilized in medicinal chemistry research programs focused on nucleoside metabolism and enzyme inhibition studies. Researchers value this material for its consistent performance in coupling reactions and its stability under various storage conditions. We support both commercial scale manufacturing and early-stage drug discovery projects with equal dedication to quality.
Quality Assurance and Storage
Quality assurance is the cornerstone of our operation. Every production batch undergoes a multi-step verification process, including raw material inspection, in-process control testing, and final product analysis. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our facilities operate under strict management systems to ensure traceability and compliance with global chemical safety standards.
Proper storage is essential to maintain the stability of this chemical intermediate. The product should be stored in a cool, dry, and well-ventilated area, protected from moisture and strong light. Containers must remain tightly closed when not in use to prevent degradation. We offer flexible packaging options, including standard cardboard drums, to suit various logistical requirements while ensuring the product arrives in perfect condition.
