Intermediates

2-Fluoroaniline

  • CAS No.348-54-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluoroaniline (CAS 348-54-9) designed for advanced organic synthesis and pharmaceutical intermediate applications with consistent quality.

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Product Technical Details

Product Overview

2-Fluoroaniline is a critical fluorinated aromatic amine that serves as a fundamental building block in modern organic chemistry. Known chemically as 2-Fluorobenzenamine, this compound is highly valued for its unique reactivity profile conferred by the ortho-positioned fluorine atom. Our manufacturing process ensures that every batch meets rigorous international standards for purity and stability, making it an ideal choice for complex synthetic pathways.

As a leading global manufacturer, we understand the importance of supply chain reliability in the chemical industry. We produce this intermediate using advanced purification techniques to minimize impurities and ensure consistent performance in downstream reactions. The presence of the fluorine substituent enhances the lipophilicity and metabolic stability of final products, which is particularly desirable in medicinal chemistry and agrochemical development.

Technical Specifications

We maintain strict quality control protocols to guarantee that our 2-Fluoroaniline meets or exceeds industry specifications. The following table outlines the key physical and chemical parameters verified during our quality assurance process.

ParameterSpecificationTypical Result
AppearanceColourless to pale yellow liquidConform
CAS Number348-54-9348-54-9
Molecular FormulaC6H6FNC6H6FN
Purity (GC)≥98.0%≥99.5%
Water Content≤0.2%0.07%
Boiling Point182-183°C182.5°C
Density1.151 g/cm³1.150 g/cm³

Industrial Applications

This fluorinated aniline derivative is extensively utilized as a key intermediate in the synthesis of various pharmaceutical agents. It serves as a precursor for constructing heterocyclic compounds and introducing fluorine motifs into drug candidates, which often improves bioavailability and binding affinity. Beyond pharmaceuticals, it finds application in the production of agrochemicals, dyes, and specialized polymers.

Researchers and process chemists value this material for its compatibility with various coupling reactions and nucleophilic substitutions. Whether used in laboratory-scale research or large-scale industrial production, our 2-Fluoroaniline provides a reliable foundation for synthesizing high-value added chemicals. The consistent quality allows for reproducible reaction outcomes, reducing waste and optimizing process efficiency.

Quality Assurance and Handling

Safety and quality are paramount in our operations. Each production lot undergoes comprehensive testing, including identification, purity analysis, and moisture content verification. We provide a Certificate of Analysis (COA) with every shipment to ensure full transparency and traceability. Our facility adheres to strict environmental and safety guidelines to manage hazardous materials responsibly.

  • Packaged in 200 kg drums for secure transport.
  • Custom packaging solutions available upon request.
  • Stored in a cool, ventilated area away from oxidizers.
  • Global shipping capabilities with documented safety data.

For bulk orders and long-term supply agreements, we offer competitive pricing and dedicated logistical support. Our team is ready to assist with technical inquiries regarding synthesis routes or application-specific requirements. Choose our 2-Fluoroaniline for a partnership built on quality, reliability, and scientific excellence.