2-Fluorobenzoic Acid
- CAS No.445-29-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluorobenzoic Acid (CAS 445-29-4) designed for pharmaceutical and agrochemical synthesis. Reliable supply with strict quality control.
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Product Overview
2-Fluorobenzoic Acid represents a vital class of fluorinated aromatic carboxylic acids extensively utilized in modern organic synthesis and industrial chemistry. As a specialized intermediate, this compound features a fluorine atom substituted at the ortho position of the benzoic acid ring, imparting unique electronic and steric properties that significantly enhance reactivity in downstream chemical transformations. Our facility produces this material under strict quality management systems to ensure consistency for pharmaceutical and agrochemical manufacturing processes worldwide.
The introduction of fluorine into organic molecules often significantly improves metabolic stability and bioavailability in final products. Consequently, high-purity 2-Fluorobenzoic Acid serves as a critical building block for developing advanced fungicides, including flutriafol, and various pharmaceutical active ingredients. We prioritize industrial purity standards to minimize impurities that could affect catalytic reactions or final product efficacy, ensuring our clients receive material suitable for sensitive synthetic routes.
Technical Specifications
Quality control is paramount in our production workflow. Each batch undergoes rigorous analytical testing using high-performance liquid chromatography (HPLC) and gas chromatography (GC) methods to verify assay purity and moisture content. The physical appearance is consistently maintained as a white crystalline powder, facilitating easy handling and dissolution in standard organic solvents. Below are the key technical parameters guaranteed for our commercial grade supply:
| Parameter | Specification |
|---|---|
| CAS Number | 445-29-4 |
| Molecular Formula | C7H5FO2 |
| Molecular Weight | 140.11 g/mol |
| Appearance | White Powder |
| Assay (HPLC) | ≥ 99.0% |
| Moisture Content | ≤ 0.5% |
| Melting Point | 122-125 °C |
| Density | 1.46 g/cm3 |
Industrial Applications
This fluorinated benzoic acid derivative is primarily employed as a key precursor in the synthesis of agrochemical fungicides. Its specific structural configuration allows for efficient coupling reactions required to produce triazole-based fungicides like flutriafol. Beyond agrochemicals, it finds utility in medicinal chemistry programs where fluorinated scaffolds are required to modulate drug pharmacokinetics and enhance binding affinity to biological targets.
- Primary intermediate for flutriafol and related fungicide production.
- Building block for pharmaceutical API synthesis involving ortho-substitution.
- Reagent for organic synthesis requiring activated aromatic carboxylic acids.
- Used in research and development for new fluorinated material discovery.
Quality Assurance and Storage
To preserve chemical integrity, 2-Fluorobenzoic Acid should be stored in a cool, well-ventilated area away from direct sunlight and moisture sources. The product is typically packaged in 25 kg drums lined with protective polyethylene bags to prevent contamination during transit. We also offer customized packaging solutions to meet specific logistical requirements for global shipping. Our commitment to compliance ensures that all shipments are accompanied by a Certificate of Analysis (COA) and safety data sheets, providing full transparency for our B2B partners.
