Intermediates

2-Fluorobenzoyl Chloride

  • CAS No.393-52-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Fluorobenzoyl Chloride (CAS 393-52-2) designed for pharmaceutical and agrochemical synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

2-Fluorobenzoyl Chloride is a vital fluorinated organic intermediate widely utilized in the synthesis of complex pharmaceutical compounds and agrochemical formulations. As an acyl chloride derivative, this compound serves as a critical building block for introducing the 2-fluorobenzoyl moiety into various molecular structures. Our manufacturing process ensures exceptional purity levels, making it suitable for demanding synthetic routes where consistency and reliability are paramount. The presence of the fluorine atom at the ortho position enhances the metabolic stability and lipophilicity of downstream products, which is highly valued in modern medicinal chemistry.

Technical Specifications

ParameterSpecification
CAS Number393-52-2
Molecular FormulaC7H4ClFO
Molecular Weight158.56 g/mol
AppearanceColorless or pale yellow transparent liquid
Purity (GC)≥ 99.00%
Density1.328 g/mL at 25 °C
Boiling Point90-92 °C at 15 mm Hg
Refractive Indexn20/D 1.536
Flash Point180 °F

Industrial Applications

This reagent is primarily employed as a key intermediate in the production of active pharmaceutical ingredients (APIs) and pesticide agents. Its high reactivity allows for efficient acylation reactions, facilitating the construction of diverse chemical architectures. In the pharmaceutical sector, it is instrumental in developing therapies requiring enhanced bioavailability. In agrochemicals, it contributes to the efficacy of novel pesticide formulations. Additionally, it finds application in the dye industry for creating specialized fluorinated colorants.

  • Essential building block for pharmaceutical API synthesis
  • Key reagent for agrochemical and pesticide development
  • Used in the production of specialized fluorinated dyes
  • Supports advanced organic synthesis and research

Quality Assurance and Storage

We adhere to rigorous quality control standards to ensure every batch meets international specifications. Each shipment is accompanied by a Certificate of Analysis (COA) verifying purity and physical properties. Due to its reactive nature as an acyl chloride, proper handling is essential. The product is moisture-sensitive and may decompose upon contact with water, releasing hydrogen chloride gas. Therefore, it is packaged in nitrogen-flushed containers to maintain stability. Storage should be in a cool, dry, and well-ventilated area, strictly separated from oxidizing agents, acids, and alkalis. Under recommended conditions, the shelf life extends up to 12 months. Our global logistics network ensures safe and timely delivery for bulk industrial requirements.