Intermediates

(2-Fluorobenzyl)hydrazine

  • CAS No.51859-98-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity (2-Fluorobenzyl)hydrazine is a critical pharmaceutical intermediate used primarily in the synthesis of Riociguat. We offer competitive bulk pricing and global logistics support.

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Product Technical Details

Product Overview

(2-Fluorobenzyl)hydrazine is a specialized organic compound characterized by the presence of a fluorine atom on the benzyl ring attached to a hydrazine functional group. This chemical structure imparts unique reactivity properties that are highly valued in modern medicinal chemistry. As a key building block, it serves as an essential precursor in the manufacturing of advanced pharmaceutical agents. Our facility produces this intermediate under strict quality control standards to ensure consistency and reliability for downstream synthesis processes.

The introduction of fluorine into organic molecules often enhances metabolic stability and bioavailability, making fluorinated intermediates like this hydrazine derivative particularly sought after in drug development. We specialize in supplying high-grade chemical materials to pharmaceutical manufacturers and research institutions worldwide. Our commitment to excellence ensures that every batch meets rigorous specifications required for complex organic synthesis.

Technical Specifications

We maintain comprehensive quality assurance protocols for all our chemical products. The following table outlines the standard physical and chemical properties for this grade. Custom specifications may be available upon request for specific project requirements.

ParameterValue
CAS Number51859-98-4
Molecular FormulaC7H9FN2
Molecular Weight140.158 g/mol
AppearanceOff-white powder
Assay (Purity)≥98.0%
Density1.1±0.1 g/cm3
Boiling Point265.8±23.0 °C at 760 mmHg
Flash Point114.6±22.6 °C

Industrial Applications

The primary application of (2-Fluorobenzyl)hydrazine is as a critical intermediate in the synthesis of Riociguat, a soluble guanylate cyclase stimulator used in the treatment of pulmonary hypertension. The precise incorporation of this hydrazine moiety is vital for the biological activity of the final pharmaceutical product. Beyond this specific application, the compound is utilized in the development of various heterocyclic structures found in agrochemicals and specialty materials.

Our manufacturing process is optimized to minimize impurities that could interfere with subsequent reaction steps. We understand the complexities of multi-step synthesis and provide materials that facilitate smoother production workflows. Clients in the pharmaceutical sector rely on our supply chain stability to maintain their own production schedules without interruption.

Quality Assurance and Logistics

Safety and quality are paramount in our operations. Each production batch undergoes thorough analysis using advanced techniques such as HPLC and NMR to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with agreed specifications. We package our products in secure 25 kg drums, with options for custom packaging to suit specific logistical needs.

Proper storage is essential to maintain product integrity. We recommend storing this chemical in a cool, ventilated place away from incompatible substances. Our global logistics network ensures timely delivery to major industrial hubs. For inquiries regarding bulk pricing, technical data sheets, or custom synthesis capabilities, please contact our sales team. We are dedicated to supporting your research and manufacturing goals with reliable chemical solutions.