2-Fluoronicotinic Acid
- CAS No.393-55-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Fluoronicotinic Acid (CAS 393-55-5) designed for advanced pharmaceutical synthesis and organic research. Reliable supply with comprehensive COA.
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Product Overview
2-Fluoronicotinic Acid is a specialized fluorinated heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. Characterized by the presence of a fluorine atom at the second position of the pyridine ring alongside a carboxylic acid functional group, this molecule offers unique reactivity profiles essential for constructing complex pharmaceutical architectures. Our facility produces this intermediate under strict quality control protocols to ensure consistency across batches, supporting research and development teams in the discovery of novel therapeutic agents.
The introduction of fluorine into organic molecules is a strategic move in drug design, often enhancing metabolic stability, bioavailability, and binding affinity. As a key precursor, 2-Fluoronicotinic Acid enables chemists to explore diverse chemical spaces efficiently. We are committed to supplying this material with high purity standards to facilitate smooth downstream reactions without the interference of impurities that could compromise yield or safety.
Key Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Fluoronicotinic Acid |
| CAS Number | 393-55-5 |
| Molecular Formula | C6H4FNO2 |
| Molecular Weight | 141.10 g/mol |
| Appearance | Light Yellow Crystalline Powder |
| Purity | ≥98.0% |
| Melting Point | 161-165 °C |
| Density | 1.706 g/cm3 |
| Boiling Point | 278.6 °C at 760 mmHg |
Industrial Applications
This compound is predominantly utilized as a pharmaceutical intermediate in the synthesis of various bioactive molecules. The carboxylic acid moiety allows for versatile derivatization, including amide coupling and esterification, which are fundamental steps in creating peptide mimetics and small molecule drugs. Additionally, the fluorine substituent provides opportunities for nucleophilic aromatic substitution, enabling the construction of more complex heterocyclic systems required in advanced therapeutic areas.
Beyond pharmaceuticals, this chemical finds applications in agrochemical research and material science where fluorinated pyridines are valued for their electronic properties and stability. Our production process is optimized to deliver industrial purity suitable for large-scale manufacturing processes, ensuring that clients receive a product that meets the rigorous demands of commercial synthesis.
Quality Assurance and Storage
- Each batch is accompanied by a Certificate of Analysis (COA) verifying identity and purity.
- Packaged in 25 kg drums to ensure stability during international shipping.
- Store in a tightly closed container in a cool, dry, and well-ventilated area.
- Protect from moisture and incompatible materials to maintain chemical integrity.
- Our quality management system ensures traceability and compliance with global safety standards.
We understand the importance of supply chain reliability in the chemical industry. As a global manufacturer, we offer competitive bulk pricing and technical support to assist with your synthesis route planning. Choose our 2-Fluoronicotinic Acid for your next project and benefit from our dedication to quality, safety, and customer satisfaction.
