Intermediates

2-Fluorophenyl Isothiocyanate

  • CAS No.38985-64-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Fluorophenyl Isothiocyanate for organic synthesis. Reliable supply for pharmaceutical research and industrial applications.

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Product Technical Details

Product Overview

2-Fluorophenyl Isothiocyanate is a highly versatile organic compound widely recognized for its significant role in modern chemical synthesis and medicinal chemistry. As a key building block, this fluorinated isothiocyanate derivative offers exceptional reactivity, making it indispensable for researchers and industrial chemists focused on developing advanced molecular structures. The presence of the fluorine atom at the ortho position enhances the electronic properties of the aromatic ring, facilitating specific nucleophilic substitutions and cyclization reactions required in complex synthetic pathways. This unique structural feature allows for the precise modulation of biological activity in downstream pharmaceutical candidates.

Our manufacturing process ensures consistent quality and high purity levels, catering to the stringent demands of pharmaceutical research and agrochemical development. We understand the critical nature of supply chain reliability in the chemical industry, which is why we maintain robust production capabilities to support both laboratory-scale experiments and large-scale industrial requirements. Sourcing high-quality intermediates is fundamental to the success of any synthesis project, and our commitment to excellence ensures that every batch meets rigorous international standards.

Technical Specifications

Parameter Value
CAS Number 38985-64-7
Molecular Formula C7H4FNS
Molecular Weight 153.18 g/mol
Purity (Assay) ≥99.0%
Appearance Colorless to pale yellow liquid
Boiling Point 104 °C (12 mmHg)
Density 1.248 g/cm³
Flash Point 97 °C

Industrial Applications

This compound serves as a crucial intermediate in the synthesis of various heterocyclic compounds, including thioureas and thiazoles, which are foundational structures in medicinal chemistry. The isothiocyanate functional group reacts readily with amines to form thiourea derivatives, a common strategy in drug discovery programs targeting enzyme inhibition. The fluorine substituent often improves metabolic stability and bioavailability in final drug products, making this intermediate particularly valuable.

  • Pharmaceutical Intermediates: Used in the development of novel therapeutic agents requiring fluorinated aromatic scaffolds for enhanced potency.
  • Agrochemical Research: Employed in the synthesis of pesticides and herbicides where specific chemical stability and environmental profile are required.
  • Material Science: Utilized in the creation of specialized polymers and functional materials with unique electronic and optical properties.
  • Chemical Biology: Applied in probe development for studying protein interactions and cellular mechanisms.

Quality Assurance and Storage

Every batch of 2-Fluorophenyl Isothiocyanate undergoes rigorous quality control testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. We provide a Certificate of Analysis (COA) with each shipment to ensure transparency and compliance with international standards. Proper storage is essential to maintain product integrity over time. The material should be stored in a cool, ventilated area away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent degradation due to hydrolysis or oxidation, which can compromise reaction yields.

We offer flexible packaging options, including 200 kg drums, to accommodate diverse logistical needs. Our global shipping network ensures timely delivery to research facilities and manufacturing plants worldwide, adhering to all safety regulations for hazardous chemicals. For specific technical inquiries or custom synthesis requirements, our expert team is available to provide comprehensive support and documentation. Partner with us for reliable supply and premium quality chemical intermediates.