Intermediates

2-Fluoropyridine

  • CAS No.372-48-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Fluoropyridine for pharmaceutical and agrochemical synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

2-Fluoropyridine is a premier heterocyclic building block extensively utilized in modern organic synthesis and medicinal chemistry. As a fluorinated derivative of pyridine, this compound serves as a critical intermediate for the development of advanced pharmaceutical agents and agrochemical formulations. The introduction of a fluorine atom at the ortho-position significantly alters the electronic properties of the pyridine ring, enhancing metabolic stability and bioavailability in downstream drug candidates. Our manufacturing facility produces this reagent with stringent quality controls to ensure consistency across large-scale production batches.

The strategic value of 2-Fluoropyridine lies in its versatility as a nucleophilic substitution partner. It enables chemists to construct complex molecular architectures efficiently. Whether used in cross-coupling reactions or as a precursor for heterocyclic ring formation, this material provides a reliable foundation for research and industrial applications. We are committed to supplying high-grade chemical intermediates that meet the rigorous demands of global pharmaceutical and chemical industries.

Technical Specifications

Our production process adheres to international quality standards, ensuring that every batch of 2-Fluoropyridine meets or exceeds the specified purity requirements. We utilize advanced distillation and purification techniques to remove impurities and moisture, guaranteeing optimal performance in sensitive synthetic reactions. The following table outlines the key physical and chemical properties verified by our quality assurance team.

ParameterSpecification
CAS Number372-48-5
Molecular FormulaC5H4FN
Molecular Weight97.090 g/mol
AppearanceColourless liquid
Assay (Purity)≥99.0%
Moisture Content≤0.5%
Density1.1±0.1 g/cm3
Boiling Point125.9±13.0 °C at 760 mmHg
Flash Point28.3±0.0 °C

Industrial Applications

This fluorinated pyridine derivative is primarily employed as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its unique reactivity profile makes it suitable for creating kinase inhibitors, antiviral agents, and other therapeutic compounds where metabolic stability is paramount. Additionally, the agrochemical sector leverages this building block for developing novel herbicides and pesticides that require specific electronic characteristics for target engagement.

Beyond life sciences, 2-Fluoropyridine finds applications in materials science and fine chemical synthesis. It acts as a versatile precursor for ligands in catalysis and functional materials. Our global clientele relies on our consistent supply chain to maintain their production schedules without interruption. We support various scales of operation, from laboratory research quantities to bulk industrial procurement.

Quality Assurance and Storage

Safety and quality are the cornerstones of our operation. Each drum of 2-Fluoropyridine is accompanied by a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Our packaging options include standard 200 kg drums, with flexibility to accommodate specific customer requirements for bulk shipping. Proper handling procedures should be followed due to the flammable nature of the liquid.

For optimal preservation, the product should be stored in a cool, ventilated place away from direct sunlight and incompatible materials. Containers must be kept tightly closed when not in use to prevent moisture absorption and contamination. Our logistics team ensures secure global shipping, complying with all relevant transportation regulations for hazardous chemicals. Contact our sales team today for competitive bulk pricing and technical support regarding your synthesis projects.