2-Hydroxy-3-trifluoromethylpyridine
- CAS No.22245-83-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Hydroxy-3-trifluoromethylpyridine (CAS 22245-83-6) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical research.
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Product Overview
Our company is pleased to present high-quality 2-Hydroxy-3-trifluoromethylpyridine, a specialized fluorinated heterocyclic compound essential for modern organic synthesis. This chemical building block, identified by CAS number 22245-83-6, is manufactured under strict quality control standards to ensure consistency and reliability for industrial and research applications. As a key intermediate, it plays a pivotal role in the development of complex molecular structures used in pharmaceuticals and agrochemicals.
The introduction of a trifluoromethyl group onto the pyridine ring significantly enhances the lipophilicity and metabolic stability of resulting compounds. This makes our 2-Hydroxy-3-trifluoromethylpyridine an invaluable asset for medicinal chemists aiming to optimize drug candidates. We prioritize purity and structural integrity, delivering a product that meets the rigorous demands of contemporary chemical research and large-scale production environments.
Technical Specifications
We maintain transparent and detailed specifications to guarantee product performance. Each batch undergoes comprehensive analytical testing using advanced instrumentation such as HPLC and NMR to verify identity and purity levels. The physical properties listed below represent the standard parameters for our commercial grade material.
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Hydroxy-3-trifluoromethylpyridine |
| CAS Number | 22245-83-6 |
| Molecular Formula | C6H4F3NO |
| Molecular Weight | 163.097 |
| Appearance | Off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 150-153°C |
| Boiling Point | 254.4±35.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
Industrial Applications
This fluorinated pyridine derivative serves as a versatile intermediate in the synthesis of various bioactive molecules. Its primary application lies in the pharmaceutical industry, where it is utilized as a starting material for constructing more complex heterocyclic systems. The presence of the hydroxy and trifluoromethyl groups offers multiple sites for functionalization, allowing chemists to derive a wide range of downstream products.
- Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and other therapeutic agents.
- Agrochemical Development: Employed in the creation of novel pesticides and herbicides requiring enhanced stability.
- Material Science: Utilized in the development of specialized organic materials with specific electronic properties.
- Research and Development: Essential for academic and industrial labs focusing on fluorine chemistry.
Quality Assurance And Storage
Quality is the cornerstone of our manufacturing process. We implement a robust quality management system that covers every stage from raw material sourcing to final product packaging. Every shipment is accompanied by a Certificate of Analysis (COA) to confirm compliance with stated specifications. Our logistics team ensures secure packaging to prevent contamination or degradation during transit.
For optimal stability, store this product in a cool, ventilated place away from direct sunlight and moisture. The recommended packaging is 25 kg per drum, though we offer flexible packaging solutions to meet specific customer requirements. Proper handling procedures should be followed to maintain the integrity of the chemical structure. By choosing our 2-Hydroxy-3-trifluoromethylpyridine, you are selecting a partner committed to safety, quality, and timely delivery for your global supply chain needs.
