Intermediates

2-Hydroxy-5-bromopyridine

  • CAS No.13466-38-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Hydroxy-5-bromopyridine (CAS 13466-38-1) designed for pharmaceutical and agrochemical synthesis. Reliable bulk supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

2-Hydroxy-5-bromopyridine is a versatile heterocyclic compound widely recognized for its critical role in advanced organic synthesis. As a key building block, this chemical intermediate facilitates the construction of complex molecular structures required in various industrial sectors. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and development teams as well as large-scale production facilities.

This pyridine derivative features a bromine substituent at the fifth position and a hydroxyl group at the second position, providing unique reactivity profiles for nucleophilic substitution and cross-coupling reactions. The stability and solubility characteristics of this compound allow for seamless integration into diverse synthetic routes.

Technical Specifications

We adhere to strict quality control protocols to guarantee that every batch meets or exceeds industry standards. The following table outlines the key physical and chemical properties of our premium grade material.

ParameterSpecification
CAS Number13466-38-1
Molecular FormulaC5H4BrNO
Molecular Weight173.99 g/mol
Purity≥98.0%
AppearanceOff-white to yellow-brown crystalline powder
Melting Point180-183 °C
Boiling Point305.9 °C at 760 mmHg
Density1.776 g/cm3

Industrial Applications

The primary utility of 2-Hydroxy-5-bromopyridine lies in its function as a precursor for high-value chemicals. It is extensively utilized in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) where heterocyclic motifs are essential for biological activity. Additionally, this compound serves as a vital intermediate in the agrochemical sector, contributing to the development of novel pesticides and herbicides.

Beyond life sciences, this material finds application in the dye and fragrance industries. Its chemical structure allows for modifications that yield specific color properties or aromatic profiles. Key advantages for process chemists include:

  • High reactivity in palladium-catalyzed coupling reactions.
  • Excellent stability under standard storage conditions.
  • Compatible with various solvent systems for flexible processing.
  • Consistent batch-to-batch reproducibility for scale-up.

Quality Assurance and Logistics

Our commitment to excellence extends beyond production. Each shipment is accompanied by a Certificate of Analysis (COA) verifying purity and physical constants. We package the product in 25kg drums, though custom packaging solutions are available to meet specific logistical requirements. To maintain integrity, the material should be stored in well-closed, light-resistant, and airtight containers in a cool, dry environment.

As a global manufacturer, we prioritize reliable supply chains and timely delivery. Whether you require sample quantities for evaluation or bulk volumes for commercial manufacturing, our team is equipped to support your project needs with competitive pricing and technical expertise.