Intermediates

2-Iodo-1,3-dimethylbenzene

  • CAS No.608-28-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Iodo-1,3-dimethylbenzene (CAS 608-28-6) designed for advanced organic synthesis and cross-coupling reactions. Available in bulk quantities with full documentation.

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Product Technical Details

Product Overview

2-Iodo-1,3-dimethylbenzene, also known by its synonyms such as 2,6-dimethyl iodobenzene, is a specialized aryl halide compound widely utilized in the field of advanced organic synthesis. As a critical building block, this chemical serves as a foundational component for constructing complex molecular architectures required in pharmaceutical research, agrochemical development, and material science applications. Our facility ensures that every batch meets rigorous international standards for purity and consistency, making it a reliable choice for large-scale industrial processes.

This compound is characterized by its distinct physical properties, including a specific density and boiling point that facilitate precise handling during reaction setups. The presence of the iodine substituent on the aromatic ring significantly enhances its reactivity in metal-catalyzed coupling reactions, allowing chemists to efficiently form carbon-carbon bonds. This reactivity profile makes it an indispensable reagent for laboratories and manufacturing plants focused on developing novel therapeutic agents or functional materials.

Chemical Properties and Specifications

Understanding the physicochemical characteristics of 2-Iodo-1,3-dimethylbenzene is essential for safe and effective utilization. The substance typically presents as a pink-brown to red transparent liquid at standard temperature and pressure. Its molecular structure, defined by the formula C8H9I, contributes to a molecular weight of approximately 232.06 g/mol. The high assay value ensures minimal impurities that could interfere with sensitive catalytic cycles.

ParameterValue
CAS Number608-28-6
Molecular FormulaC8H9I
Molecular Weight232.061
AppearancePink-brown to red transparent liquid
Assay≥98.0%
Density1.6±0.1 g/cm3
Boiling Point227.5±9.0 °C at 760 mmHg
Flash Point98.1±7.7 °C
Refractive Index1.593

Industrial Applications

The primary utility of this iodinated aromatic compound lies in its role as a versatile intermediate. It is extensively employed in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are pivotal in the synthesis of biaryl structures found in many active pharmaceutical ingredients (APIs). Additionally, the compound is used in the development of agrochemicals where specific substitution patterns on the benzene ring are required to achieve desired biological activity.

Beyond pharmaceuticals, 2-Iodo-1,3-dimethylbenzene finds application in the creation of organic light-emitting diodes (OLEDs) and other electronic materials where precise molecular engineering is necessary. The high purity grade we provide ensures that downstream products meet the strict quality controls required in high-tech industries. Researchers value this material for its consistent performance batch-to-batch, reducing the risk of failed experiments or production delays.

Quality Assurance and Packaging

We maintain a robust quality management system to guarantee the integrity of our chemical products. Each shipment of 2-Iodo-1,3-dimethylbenzene is accompanied by a comprehensive Certificate of Analysis (COA), detailing the results of our internal testing protocols. Our manufacturing process adheres to safety and environmental regulations, ensuring that the product is produced responsibly.

  • Strict quality control testing for purity and identity.
  • Secure packaging to prevent leakage and contamination.
  • Flexible packing options including 200 kg drums or custom requirements.
  • Storage recommendations include keeping the container in a cool, ventilated place.
  • Global logistics support for timely delivery to international clients.

For businesses seeking a reliable supply chain partner for organic intermediates, our commitment to quality and service makes us a preferred manufacturer. Contact our technical sales team today to discuss your specific volume requirements and receive a competitive bulk price quote.