Intermediates

2-Mercapto-4-methyl-5-thiazoleacetic acid

  • CAS No.34272-64-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Mercapto-4-methyl-5-thiazoleacetic acid (CAS 34272-64-5) designed for pharmaceutical synthesis. Ideal intermediate for cefodizime production with ≥98.0% purity assurance.

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Product Technical Details

Product Overview

2-Mercapto-4-methyl-5-thiazoleacetic acid stands as a pivotal chemical building block within the modern pharmaceutical landscape. This sophisticated thiazole derivative is engineered to meet the rigorous demands of advanced organic synthesis, particularly in the creation of beta-lactam antibiotics. Our manufacturing process ensures that every batch delivers exceptional consistency, making it a reliable choice for large-scale production environments where chemical integrity is paramount.

The compound features a unique molecular structure that combines a thiazole ring with a mercapto group and an acetic acid side chain. This specific configuration provides high reactivity and stability under controlled conditions, facilitating efficient coupling reactions during drug synthesis. As a key precursor, it plays an indispensable role in constructing complex molecular architectures required for next-generation therapeutic agents.

Technical Specifications

ParameterValue
CAS Number34272-64-5
Molecular FormulaC6H7NO2S2
Molecular Weight189.26 g/mol
Purity≥98.0%
AppearancePale yellow to pale beige solid
Melting Point207°C
Density1.52 g/cm³
Boiling Point363.4°C

Industrial Applications

The primary application of this high-grade intermediate lies in the synthesis of cefodizime, a third-generation cephalosporin antibiotic. In this context, the purity of the starting material directly influences the yield and quality of the final active pharmaceutical ingredient. Impurities at the intermediate stage can lead to costly downstream purification challenges or compromise the safety profile of the finished medication.

Beyond antibiotic production, this thiazole derivative serves as a valuable tool in medicinal chemistry research. Scientists utilize it to explore new structure-activity relationships within heterocyclic compounds. Its well-defined physical properties, such as a sharp melting point and consistent density, allow for precise process control during reaction scaling. This reliability reduces variability in manufacturing batches, ensuring compliance with strict regulatory standards.

Quality Assurance and Handling

We maintain a robust quality management system to guarantee the integrity of 2-Mercapto-4-methyl-5-thiazoleacetic acid. Each production lot undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to verify chemical identity and purity levels. A Certificate of Analysis (COA) is provided with every shipment, offering full transparency regarding specifications and test results.

Proper handling is essential to maintain product stability. The material should be stored in a cool, ventilated area away from direct sunlight and moisture. Packaging is available in 25 kg drums, with customization options to suit specific logistical requirements. Our team adheres to global safety protocols during packing and dispatch, ensuring the product arrives in optimal condition for immediate use in your synthesis workflows.

Why Partner With Us

Choosing our facility means securing a supply chain backed by decades of chemical manufacturing expertise. We offer competitive bulk pricing without compromising on quality, making us a preferred partner for both research institutions and commercial pharmaceutical producers. Our commitment to timely delivery and technical support ensures that your production schedules remain uninterrupted. Contact us today to discuss your specific requirements for this critical pharmaceutical intermediate.