2-Methyl-4-[(2-methylbenzoyl)amino]benzoic acid

Product Overview

2-Methyl-4-[(2-methylbenzoyl)amino]benzoic acid is a high-value aromatic carboxylic acid derivative widely employed as a critical building block in advanced pharmaceutical synthesis. With a molecular formula of C16H15NO3 and a molecular weight of 269.30 g/mol, this compound features a structurally complex scaffold combining benzoic acid, anilide, and ortho-substituted methyl groups—ideal for constructing bioactive molecules requiring precise steric and electronic properties.

Specifications

Industrial Applications

This compound serves primarily as a dedicated intermediate in the multi-step synthesis of Tolvaptan (CAS 150683-30-0), a selective vasopressin V2-receptor antagonist used clinically to manage hyponatremia associated with syndrome of inappropriate antidiuretic hormone secretion (SIADH). Its structural motifs enable efficient coupling and cyclization reactions under controlled conditions, ensuring high yield and reproducibility in GMP-compliant manufacturing environments.

Key advantages for industrial users include:

• Consistent batch-to-batch quality with stringent impurity profiling
• Compatibility with standard amide bond formation and aromatic functionalization protocols
• Stable physical form facilitating safe handling, storage, and transportation

Stored in a cool, well-ventilated area away from incompatible materials, the product is typically packed in 25 kg fiber drums but can be customized per client specifications. As a non-application-ready chemical entity, it is intended exclusively for research or further synthetic transformation by qualified professionals in regulated pharmaceutical supply chains.