Intermediates

2-Methyl-4-nitrobenzoic acid

  • CAS No.1975-51-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Methyl-4-Nitrobenzoic Acid (CAS 1975-51-5) designed for pharmaceutical synthesis. Reliable supply with strict quality control and global delivery.

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Product Technical Details

Product Overview

2-Methyl-4-nitrobenzoic acid is a critical organic compound widely utilized in the pharmaceutical and fine chemical industries. As a substituted benzoic acid derivative, this substance serves as a versatile building block for complex molecular synthesis. Our facility produces this chemical under stringent quality management systems to ensure consistency and reliability for downstream applications. The compound is characterized by its specific nitro and methyl substitutions on the benzene ring, which provide unique reactivity profiles essential for constructing advanced therapeutic agents.

We understand the importance of raw material quality in the production of active pharmaceutical ingredients. Therefore, our manufacturing process emphasizes high purity levels and minimal impurity profiles. This product is particularly valued in the synthesis of cardiovascular and renal therapeutic agents, acting as a key precursor in multi-step organic reactions. Our commitment to excellence ensures that every batch meets or exceeds international pharmacopoeia standards.

Technical Specifications

ParameterSpecification
CAS Number1975-51-5
Molecular FormulaC8H7NO4
Molecular Weight181.145 g/mol
AppearanceAlmost white to yellow powder
Assay (Purity)≥99.0%
Melting Point150-154 °C
Residue on Ignition≤0.5%
Density1.4±0.1 g/cm3
Boiling Point369.3±30.0 °C at 760 mmHg
Flash Point167.6±13.0 °C

Industrial Applications

This chemical intermediate plays a pivotal role in the manufacturing of specialized pharmaceutical compounds. It is notably used as a key intermediate in the synthesis of Tolvaptan, a vasopressin receptor antagonist used in the management of hyponatremia and autosomal dominant polycystic kidney disease. Beyond this specific application, the compound is employed in various organic synthesis routes where a nitro-substituted aromatic acid is required. Chemists utilize its reactivity for amidation, esterification, and reduction reactions to create diverse molecular architectures.

Our clients in the research and development sector value this product for its consistency in laboratory-scale experiments as well as pilot plant operations. The high purity ensures that side reactions are minimized, leading to improved yields in subsequent synthesis steps. Whether used for process development or commercial-scale production, this material provides a reliable foundation for chemical innovation.

Quality Assurance and Logistics

Quality control is integral to our operation. Each production batch undergoes rigorous testing using advanced analytical techniques such as HPLC, GC, and NMR to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for that lot. We maintain full traceability from raw material sourcing to final packaging, ensuring compliance with global regulatory requirements.

For logistics, the product is packaged in 25 kg drums, though we offer flexible packaging solutions tailored to customer requirements. Proper storage is essential to maintain product integrity. We recommend storing the material in a cool, ventilated place away from direct sunlight and moisture. Our supply chain team ensures safe and timely global delivery, adhering to all hazardous material transportation regulations where applicable. Partner with us for a stable supply of high-quality chemical intermediates.