2-Methyl-4-(trifluoromethoxy)aniline
- CAS No.86256-59-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Methyl-4-(trifluoromethoxy)aniline (CAS 86256-59-9) supplied for advanced organic synthesis. Ideal fluorinated building block for pharmaceutical and agrochemical applications.
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Product Overview
2-Methyl-4-(trifluoromethoxy)aniline is a specialized fluorinated aromatic amine designed for high-performance organic synthesis. As a critical building block, this compound introduces both methyl and trifluoromethoxy functional groups into complex molecular structures. These modifications are highly valued in modern medicinal chemistry and agrochemical development due to their ability to enhance metabolic stability, lipophilicity, and bioavailability of final active ingredients.
Our manufacturing process ensures consistent quality and reliability for large-scale industrial applications. We understand the stringent requirements of pharmaceutical supply chains and adhere to rigorous quality control standards throughout production. This intermediate serves as a versatile precursor for various chemical transformations, including nucleophilic substitutions and coupling reactions.
Technical Specifications
The following table outlines the key physical and chemical properties verified through our quality assurance laboratory. Each batch is accompanied by a Certificate of Analysis (COA) to guarantee compliance with specified parameters.
| Parameter | Specification |
|---|---|
| CAS Number | 86256-59-9 |
| Molecular Formula | C8H8F3NO |
| Molecular Weight | 191.15 g/mol |
| Appearance | Colourless to pale yellow clear liquid |
| Purity (GC) | ≥99.0% |
| Boiling Point | 206.9°C |
| Density | 1.288 g/cm³ |
| Refractive Index | 1.483 |
Industrial Applications
This fluorinated aniline derivative finds extensive use across multiple high-value sectors. In the pharmaceutical industry, it is utilized in the synthesis of kinase inhibitors and receptor modulators where fluorine substitution improves drug-like properties. The trifluoromethoxy group specifically offers unique electronic effects that can optimize binding affinity to biological targets.
In agrochemical formulations, this intermediate contributes to the development of advanced herbicides and fungicides. The chemical stability provided by the fluorinated moiety ensures prolonged efficacy in field conditions. Additionally, it serves as a valuable component in the production of specialty polymers and liquid crystals where specific dielectric properties are required.
Quality Assurance and Safety
We maintain a robust quality management system to ensure product integrity. Our facilities are equipped with state-of-the-art analytical instruments, including Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC), to verify purity levels. Every shipment undergoes thorough testing before release to confirm adherence to international standards.
- Strict control over impurities and by-products
- Batch traceability for full supply chain transparency
- Comprehensive stability testing under various conditions
- Compliance with global regulatory requirements
Regarding safety, this compound should be handled in accordance with standard laboratory protocols for aromatic amines. Appropriate personal protective equipment, including gloves and eye protection, is recommended during handling. Storage should be in a cool, ventilated area away from incompatible materials such as strong oxidizing agents.
Supply Chain and Logistics
As a global manufacturer, we offer flexible packaging solutions to meet diverse customer needs. Standard packing includes 200 kg drums, but custom packaging is available upon request. Our logistics network ensures timely delivery worldwide, with full documentation support for customs clearance. We are committed to providing competitive bulk pricing and technical support for process optimization.
