2-Methyltetrahydrofuran
- CAS No.96-47-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
2-Methyltetrahydrofuran is a high-purity green solvent and pharmaceutical intermediate, ideal for replacing THF in synthesis processes.
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Product Overview
2-Methyltetrahydrofuran, frequently abbreviated as 2-MeTHF, represents a significant advancement in sustainable chemical processing and organic synthesis. As a cyclic ether derived from renewable resources such as furfural, this compound serves as a superior alternative to traditional tetrahydrofuran (THF) in various demanding synthetic applications. Our manufacturing process ensures exceptional purity levels, making it an ideal choice for pharmaceutical production and industrial chemical synthesis routes. The unique physicochemical properties of this solvent facilitate improved reaction kinetics, higher operating temperatures, and simplified downstream processing compared to conventional ethers.
Produced under strict quality control standards, this chemical exhibits high stability and significantly lower peroxide formation risks than traditional solvents. It is particularly valued in the production of active pharmaceutical ingredients (APIs), including critical intermediates for antimalarial medications like Chloroquine Phosphate. The commitment to green chemistry principles underscores our production methodology, aligning with global environmental regulations and safety standards. Its partial immiscibility with water allows for easier phase separation during workup, reducing energy consumption and waste generation in large-scale operations.
Key Specifications
Our 2-Methyltetrahydrofuran meets rigorous international standards for industrial and pharmaceutical use. The following table outlines the critical quality parameters that guarantee consistent performance in your manufacturing processes. Each batch is accompanied by a Certificate of Analysis (COA) to verify compliance with these specifications and ensure reliability.
| Parameter | Specification |
|---|---|
| Appearance | Colorless transparent liquid |
| Assay (GC) | ≥99.0% |
| Water Content | ≤0.1% |
| Benzene Residue | ≤300 ppm |
| Peroxide Value | ≤0.01% |
| Refractive Index | 1.400 - 1.415 |
| Boiling Point | 79.9 °C |
Industrial Applications
This versatile solvent finds extensive application across multiple sectors of the chemical industry. Its ability to replace hazardous solvents like benzene, toluene, and chloroform makes it a preferred choice for environmentally conscious manufacturers. In organic synthesis, it supports Grignard reactions and other organometallic processes with enhanced efficiency due to its favorable boiling point and immiscibility with water. This characteristic enables simpler product isolation and solvent recovery systems.
- Pharmaceutical Intermediate: Critical component in the synthesis of Chloroquine Phosphate and other therapeutic agents requiring high purity.
- Green Solvent Replacement: Effective substitute for THF, offering easier separation, recycling capabilities, and reduced environmental impact.
- Polymer and Material Science: Used in the development of new materials, specialty polymers, and advanced organic synthesis.
- Fragrance Synthesis: Employed in the production of high-quality perfumes and aromatic compounds where solvent residue must be minimized.
Storage and Safety
Proper handling and storage are essential to maintain the integrity of 2-Methyltetrahydrofuran over time. The product should be stored in a cool, well-ventilated warehouse away from direct sunlight and heat sources. Temperatures should not exceed 37 degrees Celsius to prevent degradation or pressure buildup. As a flammable liquid, it requires strict adherence to fire safety protocols and grounding during transfer. We recommend keeping containers tightly closed when not in use to prevent moisture absorption and contamination. Our packaging options include standard 170kg drums or customized solutions based on specific logistical requirements and customer needs.
