Intermediates

2-Nitro-4-(trifluoromethoxy)aniline

  • CAS No.2267-23-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-Nitro-4-(trifluoromethoxy)aniline (CAS 2267-23-4) for advanced organic synthesis. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

2-Nitro-4-(trifluoromethoxy)aniline is a specialized fluorinated aromatic intermediate designed for complex organic synthesis applications. This compound features a unique structural combination of a nitro group and a trifluoromethoxy substituent on an aniline backbone, providing distinct electronic and steric properties valuable in medicinal chemistry and agrochemical development. Our facility produces this material under stringent quality management systems to ensure consistency across batches.

As a key building block, this chemical serves as a precursor for various downstream pharmaceutical and material science projects. The presence of the trifluoromethoxy group enhances metabolic stability and lipophilicity in final molecules, making it a preferred choice for researchers developing novel therapeutic agents. We prioritize safety and compliance in all manufacturing stages.

Technical Specifications

ParameterValue
CAS Number2267-23-4
Molecular FormulaC7H5F3N2O3
Molecular Weight222.121 g/mol
AppearanceLight yellow to yellow crystalline powder
Assay≥98.0%
Melting Point62 °C
Boiling Point284.3±35.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point125.7±25.9 °C

Quality Assurance And Manufacturing

Our production process employs advanced purification techniques to achieve high industrial purity levels. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to verify structural integrity and purity profiles. We provide comprehensive Certificates of Analysis (COA) with every shipment to support your regulatory documentation and quality control requirements.

We maintain a robust supply chain capable of fulfilling bulk orders efficiently. Our packaging options are designed to preserve product stability during transit, utilizing sealed drums that protect against moisture and light exposure. Custom packaging solutions are available upon request to meet specific logistical needs.

Industrial Applications

  • Pharmaceutical intermediate synthesis for novel drug candidates.
  • Agrochemical development requiring fluorinated aromatic structures.
  • Material science research involving specialized polymers.
  • Organic synthesis route optimization for complex molecules.
  • Custom chemical manufacturing projects requiring high purity standards.

Storage And Safety Guidelines

This product should be stored in a cool, ventilated place away from direct sunlight and heat sources. Containers must remain tightly closed when not in use to prevent contamination or degradation. Personnel handling this material should adhere to standard laboratory safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles.

In case of spillage, follow established hazardous material cleanup procedures. Ensure adequate ventilation in storage areas to maintain a safe working environment. For detailed safety information, please refer to the Safety Data Sheet (SDS) provided with your order. Our technical support team is available to assist with any handling or application inquiries.