2'-O-Methylcytidine
- CAS No.2140-72-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2'-O-Methylcytidine (CAS 2140-72-9) designed for pharmaceutical synthesis. Ideal building block for developing nucleoside derivatives and viral polymerase inhibitors.
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Product Overview
2'-O-Methylcytidine is a specialized nucleoside analog characterized by a methyl group substitution at the 2'-hydroxyl position of the ribose sugar. This structural modification enhances metabolic stability and alters binding affinity, making it a critical building block in modern medicinal chemistry. Our facility produces this compound under strict quality control protocols to ensure consistency for research and development applications.
As a key intermediate, this molecule serves as a foundational element for synthesizing complex nucleoside derivatives. These derivatives are extensively investigated for their potential as inhibitors of RNA-dependent RNA viral polymerases. The high chemical purity provided by our manufacturing process supports accurate structure-activity relationship studies and downstream drug development pipelines.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2'-O-Methylcytidine |
| CAS Registry Number | 2140-72-9 |
| Molecular Formula | C10H15N3O5 |
| Molecular Weight | 257.24 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥99.0% |
| Melting Point | 252-253°C |
| Density | 1.68 g/cm3 |
| Refractive Index | 1.677 |
Industrial Applications
This nucleoside analog is primarily utilized in the pharmaceutical and biotechnology sectors. Its primary application lies in the preparation of modified oligonucleotides and small molecule therapeutics. Researchers leverage the 2'-O-methyl modification to improve nuclease resistance and pharmacokinetic profiles of candidate drugs.
- Development of antiviral agents targeting RNA polymerase enzymes.
- Synthesis of modified RNA probes for diagnostic applications.
- Structure-activity relationship studies in nucleoside chemistry.
- Production of reference standards for analytical testing.
Quality Assurance and Packaging
We understand that reproducibility is vital in chemical synthesis. Each batch of 2'-O-Methylcytidine undergoes rigorous testing using high-performance liquid chromatography to verify purity levels. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specified parameters.
Standard packaging consists of 25 kg drums, ensuring product integrity during transit. Custom packaging solutions are available to meet specific laboratory or production line requirements. Proper storage in a cool, ventilated environment maintains the chemical stability of the powder over extended periods. Our global logistics network facilitates timely delivery to research institutions and manufacturing partners worldwide.
