2'-O-Methyluridine
- CAS No.2140-76-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2'-O-Methyluridine (CAS 2140-76-3) designed for pharmaceutical R&D. Ideal intermediate for synthesizing antiviral nucleoside derivatives.
Request Bulk PricingProduct Technical Details
Product Overview
2'-O-Methyluridine is a specialized nucleoside analog characterized by a methyl group substitution at the 2'-hydroxyl position of the ribose sugar. This structural modification enhances metabolic stability and alters binding affinity, making it a critical building block in modern medicinal chemistry. Our facility produces this compound under strict quality control standards to support global pharmaceutical research and development initiatives.
As a key intermediate, this material serves as a foundational component for the synthesis of complex oligonucleotides and modified nucleoside derivatives. Researchers utilize this compound to explore structure-activity relationships in antiviral and oncological therapeutic areas. The high purity profile ensures reliable performance in sensitive downstream synthetic reactions.
Chemical Properties and Specifications
The chemical integrity of 2'-O-Methyluridine is maintained through advanced purification processes. Below are the standard technical specifications for our industrial grade material. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with stated parameters.
| Parameter | Specification |
|---|---|
| CAS Number | 2140-76-3 |
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.23 g/mol |
| Appearance | White to off-white powder |
| Assay (HPLC) | ≥99.0% |
| Moisture Content | ≤3.0% |
| Melting Point | 154-156°C |
| Density | 1.53 g/cm3 |
Industrial Applications
This nucleoside analog is primarily employed in the preparation of modified RNA sequences and antiviral research compounds. In pharmaceutical development, it acts as a precursor for derivatives investigated for their potential to inhibit viral RNA replication mechanisms. The 2'-O-methyl modification is particularly valued for improving nuclease resistance in therapeutic oligonucleotides.
Our clients leverage this intermediate for various research purposes, including the development of diagnostic probes and the study of viral subgenomic replication models. It is essential for laboratories focusing on next-generation antisense therapies and mRNA vaccine technology enhancements.
Quality Assurance and Manufacturing
We adhere to rigorous manufacturing protocols to ensure consistency across all production batches. Our quality assurance team conducts multi-point testing throughout the synthesis route. This includes raw material verification, in-process control checks, and final product validation using high-performance liquid chromatography.
- Strict adherence to industrial purity standards.
- Comprehensive documentation and batch tracing.
- Stable supply chain for global distribution.
- Custom packaging solutions available upon request.
Packaging and Storage
To maintain product stability, 2'-O-Methyluridine is packaged in sealed containers protected from moisture and light. Standard packaging includes 25 kg drums, though we accommodate specific customer requirements for smaller research quantities or bulk industrial shipments. Storage recommendations include keeping the material in a cool, ventilated environment away from incompatible substances.
Partner with us for reliable supply of high-quality chemical intermediates. Contact our sales team for current bulk pricing, lead times, and sample requests. We are committed to supporting your research goals with premium materials and exceptional service.
