Intermediates

2-Propyl-1H-imidazole-4,5-dicarboxylic acid

  • CAS No.58954-23-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-Propyl-1H-imidazole-4,5-dicarboxylic acid (CAS 58954-23-7) designed for pharmaceutical API synthesis. Reliable bulk supply with comprehensive COA.

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Product Technical Details

Product Overview

2-Propyl-1H-imidazole-4,5-dicarboxylic acid is a critical heterocyclic building block utilized extensively in the pharmaceutical industry. As a key intermediate, it plays a pivotal role in the multi-step synthesis of advanced antihypertensive agents. Our manufacturing process ensures consistent molecular integrity and high chemical purity, meeting the rigorous demands of modern drug development pipelines.

This compound features a stable imidazole core substituted with a propyl group and dicarboxylic acid functionalities. These structural characteristics make it an ideal precursor for constructing complex active pharmaceutical ingredients (APIs). We prioritize quality control at every stage of production to guarantee batch-to-batch consistency.

Key Specifications

ParameterSpecification
Chemical Name2-Propyl-1H-imidazole-4,5-dicarboxylic acid
CAS Number58954-23-7
Molecular FormulaC8H10N2O4
Molecular Weight198.18 g/mol
AppearanceWhite powder
Purity≥98.0%
Moisture Content≤0.2%
Total Impurities≤0.3%

Industrial Applications

The primary application of this chemical lies in the synthesis of Olmesartan medoxomil, a widely prescribed angiotensin II receptor blocker. The high purity level of our intermediate ensures efficient downstream reactions, minimizing side products and optimizing overall yield in API manufacturing. It serves as a foundational element in constructing the biphenyl-tetrazole structure common in cardiovascular therapeutics.

Beyond specific API synthesis, this imidazole derivative is valuable for research and development in medicinal chemistry. Its reactivity allows for various functional group transformations, making it a versatile tool for chemists designing novel therapeutic candidates targeting metabolic and cardiovascular conditions.

Quality Assurance and Packaging

We adhere to strict quality management systems to maintain product integrity. Each batch undergoes comprehensive analysis using HPLC and NMR spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, detailing test results against established specifications.

  • Packaged in 25kg cardboard drums for optimal protection.
  • Custom packaging solutions available upon request.
  • Stored in cool, dry conditions away from direct light.
  • Containers are well-closed to prevent moisture absorption.

Our logistics network ensures timely global delivery while maintaining required storage conditions during transit. We support pharmaceutical manufacturers with reliable supply chains, technical documentation, and responsive customer service to facilitate seamless production schedules.