2-Pyridinol-1-oxide
- CAS No.13161-30-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-Pyridinol-1-oxide (≥99.0% by HPLC), widely used as a condensation reagent in organic and pharmaceutical synthesis.
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Product Overview
2-Pyridinol-1-oxide is a valuable heterocyclic intermediate extensively employed in advanced organic synthesis, particularly as a condensation reagent in the construction of complex molecular architectures. With a molecular formula of C5H5NO2 and a molecular weight of 111.10 g/mol, this compound features a unique N-oxide functional group adjacent to a hydroxyl substituent on the pyridine ring, conferring distinctive reactivity and selectivity in synthetic transformations.
Specifications
| Molecular Formula | C5H5NO2 |
|---|---|
| Molecular Weight | 111.10 g/mol |
| CAS Number | 13161-30-3 |
| Appearance | Yellow brown powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 149–152°C |
| Boiling Point | 252.3°C |
| Density | 1.431 g/cm³ |
| Refractive Index | 1.554 |
| Flash Point | 100°C |
| Storage | Store in a cool, ventilated place |
| Packaging | 25 kg/drum; custom packaging available upon request |
Industrial Applications
As a specialized condensation reagent, 2-Pyridinol-1-oxide plays a critical role in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals. Its dual functionality enables efficient formation of carbon–heteroatom and carbon–carbon bonds under mild conditions. Key applications include:
- Facilitating amide and ester bond formations in peptide mimetics and small-molecule therapeutics
- Serving as a ligand precursor or directing group in transition-metal-catalyzed reactions
- Acting as a building block for nitrogen-containing heterocycles in medicinal chemistry programs
Manufactured under stringent quality control protocols, our 2-Pyridinol-1-oxide meets global regulatory standards for industrial-scale chemical production and is supported by comprehensive documentation including Certificates of Analysis (COA) and safety data sheets.
