2-Thioladenosine
- CAS No.43157-50-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-Thioladenosine (CAS 43157-50-2) designed for pharmaceutical synthesis. Ideal intermediate for Cangrelor production with strict quality control.
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Product Overview
2-Thioladenosine is a specialized nucleoside analog characterized by the substitution of a oxygen atom with a sulfur atom at the second position of the purine ring. This unique chemical structure makes it a vital building block in the synthesis of complex pharmaceutical agents, particularly within the realm of antiplatelet therapies. As a key intermediate, it serves as a foundational molecule for the production of Cangrelor, a potent P2Y12 inhibitor used in cardiovascular medicine. Our manufacturing process ensures high structural integrity and consistency, meeting the rigorous demands of modern drug discovery and development pipelines.
We understand the critical nature of purity in pharmaceutical intermediates. Therefore, our 2-Thioladenosine is produced under strictly controlled conditions to minimize impurities and ensure batch-to-batch reproducibility. This compound is essential for research institutions and pharmaceutical companies aiming to develop next-generation therapeutics targeting thrombotic disorders. By leveraging advanced organic synthesis techniques, we deliver a product that supports efficient downstream reactions and high final yields.
Technical Specifications
Quality assurance is paramount in our production facility. Each batch undergoes comprehensive analytical testing using state-of-the-art instrumentation including HPLC and NMR spectroscopy. The following table outlines the standard specifications and typical analysis results for our commercial grade 2-Thioladenosine.
| Test Item | Standard | Typical Result |
|---|---|---|
| Appearance | White to yellow powder | Conforms |
| CAS Number | 43157-50-2 | 43157-50-2 |
| Molecular Formula | C10H13N5O4S | Conforms |
| Molecular Weight | 299.31 g/mol | 299.30 |
| Purity (HPLC) | ≥98.0% | 98.9% |
| Loss on Drying | ≤0.5% | 0.31% |
| Individual Impurity | ≤1.0% | 0.9% |
| Identification | NMR Consistent | Conforms |
Industrial Applications
The primary application of 2-Thioladenosine lies in its role as a strategic intermediate for the synthesis of Cangrelor. Beyond this specific use, it serves as a valuable tool in medicinal chemistry for exploring structure-activity relationships within purine-based compounds. Researchers utilize this thio-modified nucleoside to investigate biochemical pathways involving adenosine receptors and enzymes. Its stability and reactivity profile make it suitable for various coupling reactions required in multi-step synthesis routes.
- Pharmaceutical intermediate for antiplatelet drug manufacturing.
- Research reagent for nucleoside analog development.
- Building block for specialized organic synthesis projects.
- Quality control standard for related thio-purine compounds.
Quality Assurance and Storage
We adhere to international quality management standards to ensure product safety and efficacy. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results for the purchased batch. Proper storage is essential to maintain the chemical stability of 2-Thioladenosine. The product should be kept in a cool, ventilated environment away from direct sunlight and moisture. Packaging is available in 25 kg drums or customized according to client requirements to ensure safe global transportation. Our logistics team ensures timely delivery while maintaining the integrity of the chemical contents throughout the supply chain.
