Intermediates

2-(Trifluoromethoxy)aniline

  • CAS No.1535-75-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 2-(Trifluoromethoxy)aniline (CAS 1535-75-7) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate manufacturing.

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Product Technical Details

Product Overview

2-(Trifluoromethoxy)aniline is a specialized fluorinated aromatic amine that serves as a critical building block in modern organic synthesis. Characterized by the presence of a trifluoromethoxy group at the ortho position of the aniline ring, this compound offers unique electronic and steric properties that are highly valued in the development of advanced pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial scale production.

The incorporation of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, which is why this intermediate is frequently sought after by medicinal chemists. We maintain strict quality control protocols to guarantee that every batch meets the rigorous demands of downstream synthesis applications. This chemical is recognized for its stability and reactivity profile, facilitating efficient transformation into complex molecular structures.

Technical Specifications

Our product is supplied with comprehensive documentation, including a Certificate of Analysis (COA) for every shipment. The physical and chemical properties are tightly controlled to ensure reproducibility in your processes. We utilize advanced analytical techniques to verify composition and purity levels.

ParameterValue
Chemical Name2-(Trifluoromethoxy)aniline
CAS Number1535-75-7
Molecular FormulaC7H6F3NO
Molecular Weight177.12 g/mol
AppearanceColorless clear liquid
Purity (GC)≥99.0%
Density1.301 g/cm3
Boiling Point61-63°C
Flash Point54°C
Refractive Index1.4614-1.4634

Industrial Applications

This fluorinated aniline derivative is primarily utilized as an intermediate in the synthesis of complex organic molecules. Its specific substitution pattern allows for versatile coupling reactions, including nucleophilic substitutions and metal-catalyzed cross-couplings. Key application areas include pharmaceutical intermediate synthesis where it is used in the development of novel therapeutic candidates. It also serves as a precursor for high-performance pesticides and herbicides in agrochemical production. Additionally, it is employed in the creation of specialized polymers and liquid crystals within materials science.

The versatility of this compound makes it a staple in R&D laboratories and large-scale manufacturing facilities alike. Chemists value this reagent for its ability to introduce fluorine content efficiently, which is a key strategy in modern drug design to improve pharmacokinetic properties.

Quality Assurance and Safety

We adhere to international safety standards and regulatory compliance guidelines. Each production batch undergoes rigorous testing using gas chromatography and other analytical methods to verify purity and identity. Safety data sheets (SDS) are provided with all orders to ensure safe handling and storage within your facility. Proper personal protective equipment (PPE) should be worn when handling this chemical. It should be used in a well-ventilated area to avoid inhalation of vapors. Our quality management system ensures traceability from raw materials to finished goods.

Packaging and Logistics

To maintain product integrity during transit, 2-(Trifluoromethoxy)aniline is packaged in secure 200 kg drums. Custom packaging solutions are available upon request to accommodate specific logistical requirements. We offer global shipping services with reliable tracking and timely delivery to support your supply chain needs. Storage recommendations include keeping the container in a cool, ventilated place away from direct sunlight and incompatible materials. By choosing our company as your supplier, you gain access to a reliable partner committed to quality, safety, and customer satisfaction.