Intermediates

2-(Trifluoromethoxy)benzaldehyde

  • CAS No.94651-33-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-(Trifluoromethoxy)benzaldehyde is a premium fluorinated intermediate designed for complex pharmaceutical and agrochemical synthesis applications.

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Product Technical Details

Product Overview

2-(Trifluoromethoxy)benzaldehyde represents a critical fluorinated building block within the realm of advanced organic synthesis. As a specialized aromatic aldehyde, this compound serves as an essential precursor for the development of novel pharmaceutical agents and agrochemical formulations. The incorporation of the trifluoromethoxy group significantly enhances the metabolic stability and lipophilicity of final drug candidates, making it a preferred choice for medicinal chemists aiming to optimize bioavailability and pharmacokinetic profiles in new therapeutic entities.

Our manufacturing facility employs state-of-the-art fluorination technologies to ensure consistent quality and reliability. This chemical is particularly valued in modern drug discovery programs where fluorine substitution is used to modulate electronic properties and improve binding affinity to biological targets. We understand the critical nature of supply chain stability for research and production teams, which is why we maintain robust inventory levels to support both small-scale laboratory research and large-scale industrial production needs.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. Each batch undergoes rigorous analytical testing to confirm compliance with specified physical and chemical parameters. The following table outlines the key technical specifications guaranteed for this product:

ParameterSpecification
CAS Number94651-33-9
Molecular FormulaC8H5F3O2
Molecular Weight190.12 g/mol
AppearanceColorless liquid
Purity≥99.0%
Density1.332 g/cm³
Boiling Point77°C
Flash Point67.2°C
Refractive Index1.454

These precise physical properties facilitate smooth integration into various reaction pathways. The high refractive index and controlled boiling point indicate high purity levels, which is crucial for downstream reactions where impurities could catalyze unwanted side reactions or reduce overall yield. Our quality assurance team utilizes gas chromatography and high-performance liquid chromatography to verify these metrics before release.

Industrial Applications

Primarily utilized as an intermediate, this chemical finds extensive application in the synthesis of complex heterocyclic compounds. It is widely employed in the production of kinase inhibitors, antifungal agents, and specialized polymers. The versatility of the aldehyde functionality allows for diverse chemical transformations, including reductive amination, condensation reactions, and Grignard additions. In the agrochemical sector, it serves as a key component in developing next-generation pesticides with improved environmental profiles.

Furthermore, the trifluoromethoxy moiety is increasingly recognized for its ability to block metabolic hot spots in drug molecules, thereby extending half-life and reducing dosage requirements. This makes our product highly relevant for companies focused on developing long-acting therapeutics. We support clients across the pharmaceutical, biotechnology, and material science sectors with tailored solutions that meet their specific synthetic requirements.

Quality Assurance and Safety

We adhere to strict quality management systems aligned with international standards. Every batch undergoes rigorous testing via GC and HPLC to confirm purity specifications. Storage requires cool, ventilated conditions to maintain stability away from strong oxidizing agents and moisture. We provide comprehensive safety data sheets and certificates of analysis with every shipment to ensure regulatory compliance and safe handling practices within your facility.

Supply Chain and Logistics

Packaging options are flexible to meet industrial demands, including standard drums and custom containers based on client requirements. Our global logistics network ensures timely delivery to major chemical hubs worldwide. We offer competitive bulk pricing structures for long-term partners and provide dedicated technical support to assist with process optimization. Contact our sales team today to discuss your specific volume needs and request a sample for evaluation.