2-(Trifluoromethoxy)benzonitrile
- CAS No.63968-85-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 2-(Trifluoromethoxy)benzonitrile (CAS 63968-85-4) designed for advanced organic synthesis. Reliable supply with ≥98.0% assay for pharmaceutical and agrochemical intermediate applications.
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Product Overview
2-(Trifluoromethoxy)benzonitrile represents a high-value fluorinated intermediate essential for modern organic synthesis. As a specialized chemical entity, this compound features a unique trifluoromethoxy group attached to the ortho position of a benzonitrile ring. This structural configuration imparts distinct electronic and steric properties, making it an indispensable building block for the development of advanced pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and reliability for large-scale industrial applications. The introduction of fluorine atoms into organic molecules is a strategic approach in medicinal chemistry to enhance metabolic stability and bioavailability.
In the competitive landscape of fine chemicals, purity and stability are paramount. We employ rigorous quality control protocols to guarantee that every batch meets or exceeds the specified assay requirements. The presence of the trifluoromethoxy moiety enhances lipophilicity and metabolic stability in downstream drug candidates, which is why this intermediate is highly sought after by research laboratories and production facilities worldwide. We are committed to supplying this material with full traceability and comprehensive technical support. Our analytical team utilizes advanced chromatography techniques to verify composition and ensure minimal impurity profiles.
Key Features and Advantages
- High Chemical Purity: Assay levels consistently maintained at or above 98.0% to minimize impurities in subsequent reaction steps.
- Robust Supply Chain: Established production capacity ensures timely delivery for both pilot-scale and commercial manufacturing needs.
- Technical Expertise: Our team provides detailed synthesis route guidance and safety data to optimize your process efficiency.
- Customization Options: Flexible packaging solutions available to accommodate specific logistical requirements and storage conditions.
- Global Compliance: Manufactured in facilities adhering to strict environmental and safety standards for international trade.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-(Trifluoromethoxy)benzonitrile |
| CAS Number | 63968-85-4 |
| Molecular Formula | C8H4F3NO |
| Molecular Weight | 187.119 g/mol |
| Appearance | Colorless to light yellow liquid |
| Assay (Purity) | ≥98.0% |
| Boiling Point | 201.6±35.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 75.7±25.9 °C |
| Refractive Index | 1.461 |
Industrial Applications
This fluorinated nitrile derivative serves as a critical precursor in the synthesis of complex organic molecules. Its primary application lies in the pharmaceutical industry, where it is utilized to introduce trifluoromethoxy groups into bioactive compounds. This modification often improves the pharmacokinetic profile of drug candidates. Additionally, it finds utility in agrochemical research for developing novel pesticides and herbicides with enhanced environmental stability. The compound's reactivity allows for various transformations, including reduction, hydrolysis, and cross-coupling reactions. Researchers value this intermediate for its compatibility with diverse catalytic systems and its ability to withstand harsh reaction conditions.
Storage and Handling
To maintain optimal quality, 2-(Trifluoromethoxy)benzonitrile should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent contamination or degradation. Standard safety precautions for handling organic chemicals should be observed, including the use of appropriate personal protective equipment. We provide comprehensive safety data sheets with every shipment to ensure safe handling throughout the supply chain. For bulk orders, specialized drum packaging is available to ensure integrity during transit. Our logistics partners are experienced in hazardous material transport and regulatory compliance.
