1-(Chloromethyl)-2-(trifluoromethoxy)benzene
- CAS No.116827-40-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity fluorinated intermediate designed for advanced organic synthesis applications. Available in bulk with comprehensive quality documentation.
Request Bulk PricingProduct Technical Details
Product Overview
1-(Chloromethyl)-2-(trifluoromethoxy)benzene is a specialized fluorinated organic compound serving as a critical building block in modern chemical synthesis. Characterized by the presence of a trifluoromethoxy group ortho to the chloromethyl substituent, this molecule offers unique electronic and steric properties that are highly valued in medicinal chemistry and agrochemical development. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for researchers and industrial producers seeking reliable raw materials for complex molecular construction.
The introduction of fluorine atoms into organic structures is a proven strategy to enhance metabolic stability, lipophilicity, and bioavailability in pharmaceutical candidates. This specific benzyl chloride derivative facilitates the incorporation of the trifluoromethoxy moiety into larger scaffolds through nucleophilic substitution reactions. As a dedicated intermediate, it supports the creation of diverse chemical libraries and active pharmaceutical ingredients (APIs) where precise fluorination is required.
Technical Specifications
We adhere to strict quality control protocols to guarantee that every batch meets the required chemical standards. The following table outlines the key physical and chemical properties of this product.
| Parameter | Value |
|---|---|
| Chemical Name | 1-(Chloromethyl)-2-(trifluoromethoxy)benzene |
| CAS Number | 116827-40-8 |
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Purity | ≥99.0% |
| Density | 1.596 g/cm3 |
| Refractive Index | 1.518 |
| Appearance | Colorless to pale yellow liquid |
Industrial Applications
This compound is primarily utilized as an intermediate in the synthesis of fine chemicals and pharmaceutical substances. Its reactivity profile allows for efficient alkylation processes, enabling chemists to introduce functional groups with high precision. Common applications include the development of novel therapeutics where fluorine substitution is known to improve drug-like properties. Additionally, it serves as a valuable reagent in agrochemical research for creating next-generation crop protection agents.
- Medicinal chemistry research and drug discovery programs.
- Synthesis of fluorinated polymers and advanced materials.
- Production of agrochemical intermediates and herbicides.
- Custom organic synthesis for specialized chemical projects.
Quality Assurance and Logistics
As a global manufacturer, we prioritize safety and reliability throughout the supply chain. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified purity levels. We offer flexible packaging options, including standard 25 kg drums, to accommodate various production scales. Proper storage in a cool, ventilated environment is recommended to maintain product integrity over time. Our team is ready to assist with technical inquiries and provide bulk pricing information tailored to your specific project requirements.
