Intermediates

2-(Trifluoromethyl)benzaldehyde

  • CAS No.447-61-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 2-(Trifluoromethyl)benzaldehyde liquid for advanced organic synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

2-(Trifluoromethyl)benzaldehyde is a highly valued fluorinated aromatic compound widely utilized in the field of advanced organic synthesis. As a critical building block, this chemical features a trifluoromethyl group positioned at the ortho location relative to the aldehyde functionality. The introduction of the trifluoromethyl moiety significantly enhances the lipophilicity and metabolic stability of downstream molecules, making this intermediate indispensable in modern medicinal chemistry and agrochemical development.

Our manufacturing process ensures exceptional consistency and purity levels suitable for demanding research and industrial applications. The compound is supplied as a colorless clear liquid, ready for immediate use in various synthetic routes. We adhere to rigorous quality management systems to guarantee that every batch meets or exceeds international standards for chemical intermediates.

Technical Specifications

ParameterSpecification
Chemical Name2-(Trifluoromethyl)benzaldehyde
CAS Number447-61-0
Molecular FormulaC8H5F3O
Molecular Weight174.12 g/mol
AppearanceColorless clear liquid
Purity (Assay)≥98.0%
Density1.32 g/cm3
Boiling Point70-71°C
Melting Point-40°C
Refractive Index1.466

Industrial Applications

This fluorinated aldehyde serves as a versatile precursor in the synthesis of complex pharmaceutical agents. The reactivity of the aldehyde group allows for numerous transformations, including reductive amination, oxidation to carboxylic acids, or condensation reactions to form Schiff bases. The ortho-trifluoromethyl substitution pattern is particularly sought after for creating sterically hindered structures with unique electronic properties.

Beyond pharmaceuticals, this intermediate finds application in the development of high-performance agrochemicals and functional materials. Researchers utilize this compound to introduce fluorine atoms into molecular scaffolds, thereby improving bioavailability and binding affinity in target proteins. Its stability under various reaction conditions makes it a reliable choice for multi-step synthesis protocols.

Quality Assurance and Logistics

We maintain a robust quality control framework that includes comprehensive testing via GC, HPLC, and NMR spectroscopy. Each shipment is accompanied by a Certificate of Analysis (COA) detailing all critical quality attributes. Our facility is equipped to handle large-scale production requirements while maintaining the integrity of the chemical structure.

For storage, we recommend keeping the product in a cool, ventilated area away from direct sunlight and incompatible materials. The standard packaging consists of 200 kg drums, though we offer flexible packaging solutions tailored to specific customer logistics needs. As a global manufacturer, we ensure timely delivery and secure shipping methods to protect product quality during transit.