2-(Trifluoromethyl)phenol
- CAS No.444-30-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 2-(Trifluoromethyl)phenol intermediate for pharmaceutical and agrochemical synthesis. Available in bulk with strict quality control.
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Product Overview
2-(Trifluoromethyl)phenol, also known commercially as alpha,alpha,alpha-Trifluoro-o-cresol, represents a vital fluorinated building block within the modern chemical industry. This specialized organic compound is characterized by the presence of a trifluoromethyl group attached to the ortho position of a phenol ring. Such structural features impart unique electronic and steric properties that are highly sought after in the design and synthesis of advanced functional materials. Our facility specializes in the production of this key intermediate, ensuring consistent quality and reliable supply chains for global partners engaged in complex organic synthesis.
The introduction of fluorine atoms into organic molecules is a strategic maneuver in medicinal chemistry and agrochemical development. This specific compound serves as a precursor for numerous high-value derivatives. The trifluoromethyl group enhances metabolic stability and lipophilicity, making it an indispensable tool for researchers and process chemists. We maintain rigorous production standards to guarantee that every batch meets the demanding specifications required for downstream applications in sensitive synthetic routes.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-(Trifluoromethyl)phenol |
| CAS Number | 444-30-4 |
| Molecular Formula | C7H5F3O |
| Molecular Weight | 162.11 g/mol |
| Appearance | Yellowish crystal |
| Purity | ≥99.0% |
| Melting Point | 45-46 °C |
| Boiling Point | 147-148 °C |
| Density | 1.3 g/mL at 25 °C |
| Refractive Index | 1.457 |
Industrial Applications
This fluorinated phenol derivative is primarily utilized as a critical intermediate in the pharmaceutical and agrochemical sectors. In pharmaceutical manufacturing, it acts as a foundational structure for developing novel therapeutic agents where metabolic resistance is crucial. The electron-withdrawing nature of the trifluoromethyl group allows for precise modulation of biological activity. Consequently, it is frequently employed in the synthesis of complex active pharmaceutical ingredients (APIs) targeting various physiological pathways.
In the realm of agrochemicals, this compound contributes to the formulation of advanced pesticides and herbicides. The stability provided by the fluorine substitution ensures prolonged efficacy in field conditions. Our clients leverage this material to create robust crop protection solutions that meet international regulatory standards. Whether for research and development or large-scale production, this intermediate provides the necessary chemical versatility to achieve desired molecular architectures efficiently.
Quality Assurance and Packaging
Quality is the cornerstone of our manufacturing process. Every production lot of 2-(Trifluoromethyl)phenol undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and gas chromatography (GC) to verify purity levels exceeding 99.0%. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all physical and chemical properties to ensure full transparency and compliance with your internal quality protocols.
Standard packaging consists of 25kg drums, designed to maintain product integrity during transit. However, we offer flexible packaging solutions tailored to specific customer requirements and logistical needs. Proper storage is essential to preserve the quality of this chemical. It should be kept in a tightly closed container within a cool, dry, and well-ventilated area. Care must be taken to store it away from incompatible substances to prevent any potential chemical reactions. Our global logistics network ensures timely delivery while adhering to all safety regulations for hazardous materials transport.
