(2R,3S)-N-Benzoyl-3-phenyl Isoserine
- CAS No.132201-33-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity (2R,3S)-N-Benzoyl-3-phenyl Isoserine (CAS 132201-33-3) serves as a critical chiral intermediate for Paclitaxel synthesis, available in bulk quantities with full COA.
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Product Overview
(2R,3S)-N-Benzoyl-3-phenyl Isoserine is a highly specialized chiral intermediate essential for the pharmaceutical industry, specifically utilized in the semi-synthetic production of Paclitaxel. This compound, identified by CAS number 132201-33-3, represents a critical building block in the synthesis of potent anticancer therapeutics. Our manufacturing process ensures exceptional stereochemical purity, which is vital for the efficacy and safety of the final pharmaceutical product. As a leading global manufacturer, we prioritize consistency and quality in every batch produced.
The molecular structure of this isoserine derivative requires precise control during synthesis to maintain the correct 2R,3S configuration. Deviations in chirality can significantly impact the biological activity of the downstream drug substance. Therefore, our production facilities employ advanced chromatographic separation and crystallization techniques to guarantee the integrity of the stereocenters. This commitment to quality makes our product a preferred choice for pharmaceutical companies and research institutions focused on oncology drug development.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | (2R,3S)-N-Benzoyl-3-phenyl Isoserine |
| CAS Number | 132201-33-3 |
| Molecular Formula | C16H15NO4 |
| Molecular Weight | 285.29 g/mol |
| Appearance | White powder |
| Purity | ≥99.0% |
| Melting Point | 169-172°C |
| Density | 1.316 g/cm3 |
Quality Assurance and Storage
Quality control is paramount in the production of pharmaceutical intermediates. Each batch of (2R,3S)-N-Benzoyl-3-phenyl Isoserine undergoes rigorous testing using High-Performance Liquid Chromatography (HPLC) and Nuclear Magnetic Resonance (NMR) spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing purity levels, residual solvents, and heavy metal content to ensure compliance with international regulatory standards.
To maintain stability and potency, proper storage conditions are essential. The product should be stored in a cool, ventilated area away from direct sunlight and moisture. Our standard packaging consists of 25 kg drums, which are sealed to prevent contamination during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements or smaller scale research needs.
Industrial Applications
The primary application of this compound is as a key intermediate in the synthesis of Paclitaxel, a widely used chemotherapy medication. The high purity and correct stereochemistry of our isoserine derivative facilitate efficient coupling reactions in subsequent synthesis steps, improving overall yield and reducing waste. Beyond Paclitaxel, this building block may also serve in the development of novel taxane analogs and other complex organic molecules requiring specific chiral motifs.
Why Partner With Us
As an established manufacturer with decades of experience in fine chemicals, we offer competitive bulk pricing and reliable supply chain management. Our team provides technical support to assist with synthesis route optimization and scale-up processes. We are committed to supporting global pharmaceutical innovation by delivering high-quality intermediates that meet the stringent demands of modern drug manufacturing.
