3-(2-Bromoacetyl)-5-chlorothiophene-2-sulfonamide
- CAS No.160982-11-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate for Brinzolamide synthesis. Available in bulk quantities with strict quality control and comprehensive documentation.
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Product Overview
3-(2-Bromoacetyl)-5-chlorothiophene-2-sulfonamide is a specialized organic compound primarily utilized in the pharmaceutical industry as a critical building block. This thiophene derivative features a unique structural arrangement incorporating bromoacetyl, chloro, and sulfonamide functional groups, making it highly reactive and suitable for complex synthetic pathways. Our facility produces this chemical under stringent quality management systems to ensure consistency and reliability for downstream manufacturing processes.
As a key precursor in the synthesis of advanced therapeutic agents, this intermediate undergoes rigorous purification protocols. The presence of the bromoacetyl moiety allows for versatile nucleophilic substitution reactions, while the sulfonamide group provides stability and specific electronic properties required for subsequent chemical transformations. We cater to research laboratories and industrial-scale production units requiring dependable supply chains for high-value chemical synthesis.
Technical Specifications
Our manufacturing process adheres to international standards for pharmaceutical intermediates. Each batch is tested using advanced analytical methods including HPLC and NMR to verify structural integrity and purity levels. The following table outlines the typical physical and chemical properties observed in our standard production runs:
| Parameter | Specification |
|---|---|
| CAS Number | 160982-11-6 |
| Molecular Formula | C6H5BrClNO3S2 |
| Molecular Weight | 318.60 g/mol |
| Appearance | Off-white or pale yellow powder |
| Purity | ≥99.0% |
| Melting Point | 177°C - 181°C |
| Moisture Content | ≤0.01% |
| Loss On Drying | ≤0.2% |
Industrial Applications
This compound serves as a vital intermediate in the multi-step synthesis of specific pharmaceutical active ingredients. Its primary application lies in the production pathway for Brinzolamide, a well-known therapeutic agent used in ophthalmic formulations. The high reactivity of the bromoacetyl group facilitates efficient coupling reactions, enabling chemists to construct complex molecular architectures with high yield and selectivity.
Beyond its role in ophthalmic drug synthesis, this thiophene sulfonamide derivative is explored in various organic synthesis projects requiring halogenated heterocyclic building blocks. Researchers utilize this material for developing new chemical entities where the thiophene scaffold provides essential pharmacophore characteristics. Our team supports custom synthesis requests for modified analogs based on specific project requirements.
Quality Assurance and Handling
Quality is paramount in our production facility. Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. We maintain traceability from raw material sourcing to final packaging. The product is packaged in secure 25kg cardboard drums or customized containers based on client logistics needs. Proper storage conditions are essential to maintain stability; we recommend keeping the material in a cool, dry, well-closed container away from moisture and strong light or heat sources.
Our global distribution network ensures timely delivery to clients worldwide. We comply with all relevant international shipping regulations for chemical substances. For large-scale procurement, we offer competitive bulk pricing and flexible payment terms. Our technical support team is available to assist with safety data sheets (SDS) and handling guidelines to ensure safe integration into your manufacturing processes.
