3-(4-Fluorophenyl)-1-isopropyl-1H-indole
- CAS No.93957-49-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate essential for the synthesis of Fluvastatin. Available in bulk quantities with comprehensive quality documentation and reliable global supply.
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Product Overview
3-(4-Fluorophenyl)-1-isopropyl-1H-indole is a specialized organic compound classified within the indole derivative family. This sophisticated chemical structure serves as a critical building block in the pharmaceutical industry, specifically designed for the multi-step synthesis of advanced therapeutic agents. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for large-scale pharmaceutical production.
The compound features a robust indole core substituted with a 4-fluorophenyl group and an isopropyl moiety. This specific configuration is essential for achieving the desired stereochemical and pharmacological properties in downstream drug products. We prioritize quality control at every stage of production, from raw material sourcing to final packaging, ensuring that clients receive a product that facilitates efficient and reliable synthesis workflows.
Key Specifications
To support precise formulation and reaction planning, we provide detailed physical and chemical property data. Our analytical teams verify each parameter using state-of-the-art instrumentation, including HPLC, NMR, and Mass Spectrometry. The following table outlines the standard specifications for this intermediate:
| Parameter | Value |
|---|---|
| CAS Number | 93957-49-4 |
| Molecular Formula | C17H16FN |
| Molecular Weight | 253.314 g/mol |
| Appearance | Off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Melting Point | 96-97°C |
| Boiling Point | 389.6±25.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 189.4±23.2 °C |
Industrial Applications
The primary application of 3-(4-Fluorophenyl)-1-isopropyl-1H-indole is as a key intermediate in the manufacturing of Fluvastatin, a well-known HMG-CoA reductase inhibitor used to manage cholesterol levels. The integrity of this intermediate directly influences the yield and purity of the final active pharmaceutical ingredient (API). Therefore, maintaining high assay levels and minimizing impurities is crucial for regulatory compliance and patient safety.
Beyond its specific role in statin production, this indole derivative is valuable in medicinal chemistry research and development. It serves as a versatile scaffold for exploring new biological activities and optimizing drug candidates. Our clients utilize this material for:
- Large-scale commercial synthesis of cardiovascular medications.
- Process development and optimization studies.
- Reference standard preparation for analytical testing.
- Custom organic synthesis projects requiring high-purity indole structures.
Quality Assurance and Storage
We understand that stability and consistency are paramount in pharmaceutical supply chains. Each production lot undergoes comprehensive testing, and a Certificate of Analysis (COA) is provided with every shipment. Our quality management system adheres to strict protocols to ensure traceability and reliability. For optimal preservation of chemical integrity, we recommend storing the product in a cool, ventilated environment away from direct sunlight and moisture.
Packaging is designed to protect the material during transit while accommodating various volume requirements. Standard packaging includes 25 kg drums, but we offer flexible solutions tailored to specific customer logistics needs. Whether you require sample quantities for R&D or bulk volumes for commercial manufacturing, our supply chain is equipped to deliver timely and secure shipments globally.
