Intermediates

3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile

  • CAS No.35249-62-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity pharmaceutical intermediate essential for the synthesis of Ivabradine hydrochloride, offering consistent quality for large-scale production.

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Product Technical Details

Product Overview

3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile is a specialized organic compound widely recognized for its critical role in the pharmaceutical industry. This chemical serves as a key building block in the multi-step synthesis of Ivabradine hydrochloride, a therapeutic agent used in the management of chronic heart failure and angina pectoris. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency, making it an ideal choice for pharmaceutical companies and research institutions focused on cardiovascular medication development.

As a nitrile derivative featuring a brominated dimethoxyphenyl structure, this intermediate exhibits specific reactivity profiles that are essential for downstream coupling reactions. The precise arrangement of functional groups allows for efficient transformation into active pharmaceutical ingredients (APIs) while maintaining structural integrity throughout the synthesis pathway. We prioritize quality control at every stage, from raw material sourcing to final packaging, to guarantee optimal performance in your production lines.

Technical Specifications

ParameterValue
Chemical Name3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile
CAS Number35249-62-8
Molecular FormulaC11H12BrNO2
Molecular Weight270.12 g/mol
AppearanceWhite powder
Purity≥99%
Moisture Content<0.01%
Impurity Level<0.01%
Density1.375 g/cm3
Boiling Point379.4°C at 760 mmHg
Flash Point183.3°C

Industrial Applications

The primary application of this compound lies in the synthesis of Ivabradine, where it acts as a crucial precursor. Its high purity level minimizes the formation of unwanted by-products, thereby streamlining the purification process and improving overall yield. Beyond cardiovascular therapeutics, this intermediate may also find utility in the development of other complex organic molecules requiring a brominated methoxyphenyl scaffold. Researchers value this material for its stability and predictable reaction kinetics, which facilitate scalable manufacturing processes.

Quality Assurance and Packaging

We understand that consistency is paramount in pharmaceutical manufacturing. Our facility employs advanced analytical techniques, including HPLC and GC-MS, to verify the identity and purity of each lot. Comprehensive Certificates of Analysis (COA) are provided with every shipment to ensure full traceability and compliance with regulatory requirements.

  • Packaged in 25kg cardboard drums for secure transport.
  • Custom packaging solutions available upon request.
  • Stored in cool, dry conditions away from moisture and direct light.
  • Global shipping capabilities with strict adherence to safety regulations.

Partner with us for reliable supply chain solutions and technical support tailored to your specific synthesis needs. Our team is dedicated to supporting your R&D and production goals with premium chemical intermediates.