Intermediates

3-(2-Hydroxy-3-Nitrophenyl)Benzoic Acid

  • CAS No.376591-95-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 3-(2-Hydroxy-3-Nitrophenyl)Benzoic Acid (CAS 376591-95-6) designed for pharmaceutical synthesis. High purity ≥98.0% available for bulk orders with COA.

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Product Technical Details

Product Overview

3-(2-Hydroxy-3-Nitrophenyl)Benzoic Acid is a specialized organic compound utilized extensively within the pharmaceutical manufacturing sector. This biphenyl derivative serves as a critical building block in the synthesis of advanced therapeutic agents. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream chemical processes. The compound is characterized by its distinct yellow powder appearance and high chemical stability, making it suitable for various reaction conditions encountered in medicinal chemistry.

We understand the importance of supply chain integrity in the pharmaceutical industry. As a dedicated manufacturer, we provide comprehensive documentation including Certificates of Analysis (COA) with every shipment. Our production capabilities allow us to meet both pilot-scale and commercial-scale demands, ensuring that your project timelines are met without compromise on quality.

Key Specifications

ParameterSpecification
CAS Number376591-95-6
Molecular FormulaC13H9NO5
Molecular Weight259.214 g/mol
AppearanceYellow powder
Assay (Purity)≥98.0%
Density1.5±0.1 g/cm3
Boiling Point452.2±40.0 °C at 760 mmHg
Flash Point193.8±15.8 °C
Vapour Pressure0.0±1.2 mmHg at 25°C
Index of Refraction1.669

Industrial Applications

The primary application of this chemical intermediate lies in the synthesis of Eltrombopag, a significant pharmaceutical agent. Its structural properties enable specific coupling reactions required to construct the complex biphenyl backbone found in the final active pharmaceutical ingredient. Researchers and process chemists value this material for its reactivity profile and purity levels, which minimize impurity carryover into subsequent synthesis steps.

  • Essential intermediate for thrombopoietin receptor agonist synthesis
  • Used in multi-step organic synthesis pathways
  • Compatible with various catalytic systems
  • Supports scalable manufacturing processes

Quality Assurance

Quality is the cornerstone of our manufacturing philosophy. Each batch of 3-(2-Hydroxy-3-Nitrophenyl)Benzoic Acid undergoes rigorous analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We maintain full traceability from raw material sourcing to final packaging. Our facilities adhere to international safety and environmental standards, ensuring that every product delivered meets the stringent requirements of global pharmaceutical clients. Storage recommendations include keeping the material in a cool, ventilated place to maintain optimal stability over time.