3-(2-Methoxy-3-nitrophenyl)benzoic Acid
- CAS No.376591-94-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-(2-Methoxy-3-nitrophenyl)benzoic Acid (CAS 376591-94-5) designed for pharmaceutical synthesis. Ideal intermediate for Eltrombopag production with ≥98.0% assay guarantee.
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Product Overview
3-(2-Methoxy-3-nitrophenyl)benzoic Acid is a specialized organic compound widely recognized for its critical role in advanced pharmaceutical manufacturing. Identified by CAS number 376591-94-5, this chemical substance serves as a vital building block in the synthesis of complex therapeutic agents. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical applications. The compound is characterized by its specific structural configuration, which enables precise chemical transformations required in modern drug development pipelines.
As a dedicated manufacturer, we understand the importance of molecular integrity in medicinal chemistry. This benzoic acid derivative is engineered to meet the rigorous demands of active pharmaceutical ingredient (API) synthesis. The presence of methoxy and nitro functional groups on the biphenyl scaffold provides unique reactivity profiles, making it an indispensable component for constructing specific pharmacophores. Our production processes are optimized to deliver material that supports efficient reaction pathways while minimizing impurities that could affect final drug product safety.
Key Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-(2-Methoxy-3-nitrophenyl)benzoic Acid |
| CAS Number | 376591-94-5 |
| Molecular Formula | C14H11NO5 |
| Molecular Weight | 273.24 g/mol |
| Appearance | Off-white to light brown powder |
| Assay (Purity) | ≥98.0% |
| Packaging | 25 kg/drum or customized |
Industrial Applications
The primary application of this chemical intermediate lies in the pharmaceutical sector, specifically as a precursor in the manufacturing of Eltrombopag. Eltrombopag is a well-known thrombopoietin receptor agonist used in the treatment of chronic immune thrombocytopenia and other hematological conditions. The precision required in synthesizing such medications demands raw materials of exceptional purity and structural accuracy. Our 3-(2-Methoxy-3-nitrophenyl)benzoic Acid is validated to support these high-stakes synthesis routes, ensuring that the final API meets global regulatory standards.
Beyond its specific use in Eltrombopag production, this compound serves as a versatile synthon in organic chemistry laboratories. Researchers utilize this building block for developing novel therapeutic candidates where biphenyl carboxylic acid structures are required. The stability of the nitro and methoxy substituents allows for various chemical modifications, including reduction, coupling, and esterification reactions. This versatility makes it a valuable asset for contract research organizations and pharmaceutical companies engaged in drug discovery and process development.
Quality Assurance and Storage
Quality is the cornerstone of our manufacturing philosophy. Every batch of 3-(2-Methoxy-3-nitrophenyl)benzoic Acid undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a Certificate of Analysis (COA) with every shipment, detailing purity levels, residual solvents, and heavy metal content. Our facilities adhere to international safety and environmental standards, ensuring that the production process is both sustainable and compliant with regulatory requirements.
Proper storage is essential to maintain the chemical stability of this product. We recommend storing the material in a cool, ventilated area away from direct sunlight and moisture. The standard packaging consists of 25 kg drums, which are designed to protect the powder from contamination and degradation during transit. However, we offer flexible packaging solutions to meet specific customer logistics needs. Our global supply chain ensures timely delivery to laboratories and manufacturing plants worldwide, supported by detailed documentation for customs and regulatory clearance.
Why Choose Our Product
- Consistent high purity levels exceeding 98.0% assay specifications.
- Validated synthesis route suitable for large-scale pharmaceutical production.
- Comprehensive technical support and documentation including COA and MSDS.
- Flexible packaging options to accommodate various production scales.
- Reliable global shipping with secure logistics partners.
