Intermediates

3,3,3-Trifluoro-1-propanol

  • CAS No.2240-88-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

A high-purity fluorinated alcohol intermediate essential for pharmaceutical R&D and advanced material synthesis, available in bulk quantities.

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Product Technical Details

Product Overview

3,3,3-Trifluoro-1-propanol represents a critical fluorinated building block within the realm of advanced organic synthesis. As a primary alcohol featuring a trifluoromethyl group at the terminal position, this compound offers unique physicochemical properties that are highly sought after in modern chemical manufacturing. The introduction of fluorine atoms into organic molecules is a strategic approach used to enhance metabolic stability, lipophilicity, and bioavailability in pharmaceutical candidates. Our facility specializes in the production of high-purity fluorochemicals, ensuring that every batch meets rigorous international standards for research and industrial application.

This substance serves as a versatile precursor for a wide array of downstream chemicals. The strong electron-withdrawing nature of the trifluoromethyl moiety influences the reactivity of the hydroxyl group, making it an excellent substrate for various transformation reactions. Whether utilized in the creation of novel pharmaceutical active ingredients or the development of high-performance materials, 3,3,3-Trifluoro-1-propanol provides the foundational structure necessary for innovation in chemical science.

Technical Specifications

Quality consistency is paramount in chemical manufacturing. We employ advanced analytical techniques to verify the identity and purity of each production lot. The following table outlines the key physical and chemical properties typically associated with this grade of material.

ParameterValue
CAS Number2240-88-2
Molecular FormulaC3H5F3O
Molecular Weight114.07 g/mol
AppearanceColorless liquid
Density1.294 g/cm3
Boiling Point100 °C
Flash Point37 °C
Refractive Index1.32

Industrial Applications

The utility of this fluorinated alcohol extends across multiple high-value sectors. In the pharmaceutical industry, it is frequently employed as a key intermediate in the synthesis of complex drug molecules. The fluorine content can significantly alter the pharmacokinetic profile of a drug, making this building block invaluable for medicinal chemists aiming to optimize lead compounds.

Furthermore, the agrochemical sector utilizes this reagent for the development of new pesticides and herbicides. The stability provided by the fluorine atoms helps these compounds withstand environmental degradation, ensuring effective performance in the field. Additionally, within the materials science domain, 3,3,3-Trifluoro-1-propanol is used to synthesize specialized polymers and coatings that require specific surface properties or chemical resistance. Our commitment to providing a complete fluorochemical platform allows customers to source this material alongside other necessary reagents for streamlined production.

Quality Assurance and Supply

As a dedicated manufacturer, we maintain a comprehensive quality control system that covers every stage from raw material procurement to final product storage. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters. We understand the importance of supply chain reliability for continuous manufacturing processes. Therefore, we strive to maintain robust inventory levels and offer flexible logistics solutions to meet global demand. Our team is equipped to handle bulk orders while ensuring that safety protocols regarding flammability and storage conditions are strictly adhered to throughout the distribution network.

Safety and Handling

Proper handling procedures are essential when working with fluorinated alcohols. Given the flash point of 37 °C, this material should be stored in a cool, well-ventilated area away from ignition sources. Personal protective equipment, including gloves and safety goggles, is recommended during handling to prevent skin or eye contact. We provide comprehensive safety data sheets with every order to ensure that our partners can maintain a safe working environment while leveraging the benefits of this advanced chemical intermediate.