3,3-Difluoroazetidine Hydrochloride
- CAS No.288315-03-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,3-difluoroazetidine hydrochloride, a valuable fluorinated heterocyclic building block for pharmaceutical and agrochemical R&D.
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Product Overview
3,3-Difluoroazetidine hydrochloride is a specialized fluorinated heterocyclic amine widely employed as a key intermediate in modern medicinal chemistry and agrochemical innovation. This compound features a strained azetidine ring substituted with two fluorine atoms at the 3-position, conferring enhanced metabolic stability, improved membrane permeability, and modulated pKa—properties highly sought after in the design of bioactive molecules. As a hydrochloride salt, it offers excellent crystallinity, stability, and solubility characteristics suitable for scalable synthetic processes.
Specifications
| Molecular Formula | C₃H₆ClF₂N |
|---|---|
| Molecular Weight | 129.54 g/mol |
| CAS Number | 288315-03-7 |
| Melting Point | 138–143 °C |
| Appearance | White to off-white crystalline powder |
Industrial Applications
This fluorinated building block serves critical roles across multiple high-value sectors:
- In pharmaceutical research, it acts as a versatile scaffold for constructing novel drug candidates targeting central nervous system disorders, oncology, and infectious diseases.
- In agrochemical development, its unique structure contributes to the creation of next-generation pesticides with improved environmental profiles and target specificity.
- It is also utilized in advanced materials science for designing fluorine-containing polymers and functional molecules requiring precise steric and electronic tuning.
As part of a comprehensive fluorochemical portfolio, 3,3-difluoroazetidine hydrochloride exemplifies the strategic integration of fluorine into molecular architecture to unlock new performance frontiers. Our manufacturing adheres to stringent quality control protocols, ensuring batch-to-batch consistency, full traceability, and compliance with international regulatory standards for B2B chemical supply.
