Intermediates

(3,3-Dimethyl)butyldimethylsilyl Chloride

  • CAS No.96220-76-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade silylating agent designed for pharmaceutical organic synthesis. Available in bulk quantities with strict quality control and fast global delivery.

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Product Technical Details

Product Overview

(3,3-Dimethyl)butyldimethylsilyl Chloride represents a critical silylating agent utilized extensively within modern organic synthesis workflows and pharmaceutical manufacturing sectors. As a specialized intermediate, this compound serves as a robust protecting group for hydroxyl functionalities, enabling chemists to navigate complex multi-step reactions with enhanced precision and yield optimization. Our advanced manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for large-scale pharmaceutical production and advanced research laboratories requiring high reliability and purity standards. The chemical structure provides steric bulk that enhances stability during subsequent synthetic transformations.

Technical Specifications

ParameterValue
AppearanceColorless or light yellow transparent liquid
Content (Purity)98% Minimum
CAS Number96220-76-7
Storage TemperatureBelow 25℃

Industrial Applications

This reagent is predominantly employed in the synthesis of active pharmaceutical ingredients where temporary protection of sensitive functional groups is required to prevent degradation. Its stability under various reaction conditions allows for versatile application across medicinal chemistry programs and process development scales. Furthermore, the compound facilitates the development of novel therapeutic candidates by preventing unwanted side reactions during critical synthesis stages involving strong bases or nucleophiles. Researchers value this material for its predictable reactivity profile and ease of removal under mild acidic conditions.

  • High reactivity towards hydroxyl groups
  • Stable protection under basic conditions
  • Compatible with various organic solvents
  • Efficient deprotection pathways

Packaging and Storage

To maintain optimal quality and safety, the product is supplied in fluorinated bottles for smaller quantities and industrial drums for bulk orders. Storage conditions require a cool environment below 25 degrees Celsius in original sealed containers to prevent moisture ingress which could lead to hydrolysis. The shelf life extends to one year provided storage guidelines are followed strictly. As a dangerous good classified under Class 8 plus 3, all shipments adhere to strict international safety regulations regarding corrosive and flammable materials. Proper personal protective equipment is recommended during handling.

Quality Commitment

We provide comprehensive documentation including Certificates of Analysis for every batch to ensure compliance with internal quality standards. Our global logistics network ensures timely delivery while maintaining product integrity throughout transit via approved hazardous material carriers. Customer support teams are available to assist with technical inquiries regarding usage rates and compatibility with specific solvent systems. Our quality control laboratory employs gas chromatography and nuclear magnetic resonance spectroscopy to verify identity and purity levels exceeding industry norms. Each batch undergoes rigorous testing for residual solvents and heavy metals to ensure suitability for sensitive pharmaceutical applications. We maintain full traceability from raw material sourcing to final packaging. This dedication to quality minimizes risk in downstream processing and reduces waste associated with failed reactions. Our facility operates under strict environmental management systems to reduce the ecological footprint of chemical manufacturing. Clients benefit from our scalable production capacity which can accommodate urgent rush orders without compromising safety protocols.