3,4,5-Trifluoroaniline
- CAS No.163733-96-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,4,5-Trifluoroaniline (CAS 163733-96-8) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
3,4,5-Trifluoroaniline is a highly specialized fluorinated aromatic amine that serves as a critical building block in modern organic synthesis. Characterized by the presence of three fluorine atoms on the benzene ring, this compound offers unique electronic and steric properties that are essential for the development of advanced pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity, making it an ideal choice for research and industrial scale production.
As a key intermediate, this substance facilitates the introduction of fluorine motifs into complex molecular structures. Fluorination is a strategic modification in medicinal chemistry known to enhance metabolic stability, bioavailability, and binding affinity of drug candidates. Therefore, securing a reliable supply of high-grade 3,4,5-Trifluoroaniline is vital for laboratories and production facilities focused on innovation.
Technical Specifications
We adhere to strict quality control protocols to guarantee that every batch meets rigorous international standards. The physical and chemical properties are meticulously verified through advanced analytical techniques including HPLC and GC-MS. Below are the standard specifications for our commercial grade product:
| Parameter | Specification |
|---|---|
| CAS Number | 163733-96-8 |
| Molecular Formula | C6H4F3N |
| Molecular Weight | 147.10 g/mol |
| Appearance | Colorless to light yellow transparent liquid |
| Assay (Purity) | ≥99.0% |
| Moisture Content | ≤0.2% |
| Density | 1.409 g/cm3 |
| Boiling Point | 200.4°C |
| Melting Point | 61-64°C |
Industrial Applications
The versatility of 3,4,5-Trifluoroaniline allows it to be utilized across various sectors within the chemical industry. Its primary role is as a precursor in the synthesis of more complex molecules. Key application areas include:
- Pharmaceutical Intermediates: Used in the construction of novel therapeutic compounds requiring fluorinated aromatic rings.
- Agrochemical Development: Serves as a building block for pesticides and herbicides with enhanced environmental stability.
- Material Science: Employed in the creation of specialized polymers and liquid crystals with specific electronic properties.
- Organic Synthesis: Acts as a nucleophile in substitution reactions to introduce trifluorophenyl groups.
Quality Assurance and Packaging
Our commitment to excellence extends beyond production to packaging and logistics. Each drum is sealed to prevent moisture absorption and contamination during transit. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing batch-specific test results. Custom packaging solutions are available to meet specific client requirements, ensuring safety and convenience regardless of order volume.
Storage and Handling
To maintain optimal stability, 3,4,5-Trifluoroaniline should be stored in a cool, ventilated area away from direct sunlight and heat sources. Containers must remain tightly closed when not in use. Personnel handling this chemical should follow standard safety procedures for aromatic amines, including the use of appropriate personal protective equipment (PPE) such as gloves and safety goggles. Proper ventilation is essential to avoid inhalation of vapors during processing.
