3,4,5-Trifluoronitrobenzene
- CAS No.66684-58-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity 3,4,5-Trifluoronitrobenzene for advanced organic synthesis. Reliable supply with COA.
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Product Overview
3,4,5-Trifluoronitrobenzene is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern medicinal chemistry and agrochemical development. Characterized by its unique substitution pattern, this molecule offers exceptional reactivity for nucleophilic aromatic substitution reactions. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for complex synthetic routes requiring precise fluorination.
As a leading global manufacturer, we understand the stringent requirements of pharmaceutical and fine chemical industries. This product is synthesized under strict quality control protocols to minimize impurities and ensure batch-to-batch consistency. The presence of three fluorine atoms enhances the metabolic stability and lipophilicity of downstream drug candidates, making this intermediate invaluable for developing next-generation therapeutics.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3,4,5-Trifluoronitrobenzene |
| CAS Number | 66684-58-0 |
| Molecular Formula | C6H2F3NO2 |
| Molecular Weight | 177.08 g/mol |
| Appearance | Light yellow liquid |
| Assay | ≥99.0% |
| Moisture Content | ≤0.2% |
| Density | 1.517 g/cm3 |
| Boiling Point | 208.6°C |
| Flash Point | 167°F |
| Refractive Index | 1.486 |
Industrial Applications
This fluorinated nitrobenzene derivative is primarily utilized as a key intermediate in the synthesis of quinolone antibiotics and other pharmaceutical agents. The electron-withdrawing nitro group combined with the fluorine substituents activates the aromatic ring for selective nucleophilic displacement. This property is extensively exploited in the production of active pharmaceutical ingredients (APIs) where specific fluorination patterns are required to optimize bioavailability and pharmacokinetic profiles.
Beyond pharmaceuticals, 3,4,5-Trifluoronitrobenzene finds applications in the development of advanced agrochemicals and functional materials. Researchers utilize this compound to introduce trifluorophenyl moieties into complex molecular architectures. Its stability under various reaction conditions allows for versatile synthetic transformations, including reduction to anilines or conversion to other functional groups necessary for final product formulation.
Quality Assurance and Storage
- Manufactured in ISO certified facilities with comprehensive quality management systems.
- Each batch is accompanied by a Certificate of Analysis (COA) detailing purity and physical constants.
- Packaged in 200 kg drums or customized containers based on client logistical requirements.
- Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and heat sources.
- Handling should be performed with appropriate personal protective equipment to ensure safety during transfer and usage.
We are committed to providing reliable supply chains for critical chemical intermediates. Our logistics network supports global shipping, ensuring timely delivery to research laboratories and production plants worldwide. For bulk pricing inquiries or technical support regarding synthesis routes, our expert team is available to assist with your specific project needs.
