3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile
- CAS No.276863-95-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile (CAS 276863-95-7), a key pharmaceutical intermediate for advanced serotonin modulator synthesis.
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Product Overview
3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile is a high-value, specialty organic compound widely employed as a critical building block in the synthesis of next-generation serotonergic therapeutics. With a molecular formula of C13H11ClN2O and a molecular weight of 246.69 g/mol, this indole-derived intermediate exhibits excellent reactivity and selectivity in multi-step pharmaceutical manufacturing processes.
Specifications
| Molecular Formula | C13H11ClN2O |
|---|---|
| Molecular Weight | 246.69 g/mol |
| Density | 1.314 g/cm³ |
| Boiling Point | 489.85°C at 760 mmHg |
| Flash Point | 250.053°C |
| Refractive Index | 1.624 |
| Appearance | White crystalline powder |
| Purity | ≥99% |
Industrial Applications
This compound serves as a pivotal intermediate in the production of advanced neurological therapeutics, particularly in the synthesis pathways of vilazodone-related active pharmaceutical ingredients (APIs). Its structural features—combining an electron-deficient nitrile group with a chlorinated aliphatic chain on the indole core—enable precise functionalization during complex heterocyclic assembly.
- Essential precursor for serotonin modulator APIs under strict regulatory frameworks
- Enables efficient cyclization and side-chain elaboration in GMP-compliant synthesis
- Consistent batch-to-batch quality ensures reliability in large-scale pharmaceutical manufacturing
Stored in a cool, dry, and tightly sealed container away from moisture, heat, and direct light, this intermediate maintains stability throughout extended shelf life. Packaged in 25 kg fiber drums or customized configurations per client requirements, it meets global standards for B2B chemical supply chains.
