3,4-Dichloro-2-fluoroaniline

Product Overview

3,4-Dichloro-2-fluoroaniline is a specialized halogenated aromatic amine that serves as a critical building block in modern medicinal chemistry. Identified by CAS number 886762-39-6, this compound features a unique substitution pattern on the aniline ring, providing specific reactivity profiles required for complex organic synthesis. Our facility produces this chemical under stringent quality management systems to ensure consistency across batches. The molecular structure incorporates both chloro and fluoro substituents, making it an invaluable precursor for the development of kinase inhibitors and other targeted therapeutic agents.

Key Technical Advantages

We understand that the success of downstream synthesis depends heavily on the quality of starting materials. Our manufacturing process employs advanced purification techniques to minimize impurities that could interfere with subsequent reaction steps. By maintaining tight control over reaction parameters, we deliver a product that meets the rigorous demands of pharmaceutical research and production environments. Our commitment to excellence ensures that every drum shipped conforms to the specified purity standards.

• Consistent molecular integrity for reliable reaction outcomes
• Advanced purification methods to reduce trace contaminants
• Scalable production capacity to meet global demand
• Comprehensive documentation including COA and MSDS

Detailed Specifications

Industrial Applications

This compound is primarily utilized as a key intermediate in the synthesis of Poziotinib, a potent irreversible inhibitor of EGFR and HER2 kinases. The specific arrangement of halogen atoms allows for selective coupling reactions necessary for constructing the core scaffold of such therapeutic molecules. Beyond oncology research, this aniline derivative finds utility in the preparation of various agrochemicals and functional materials where halogenated aromatic amines are required. Researchers value this material for its stability and predictable reactivity profile during nucleophilic substitution and cross-coupling processes.

Storage and Safety Handling

Proper storage conditions are vital to maintain the chemical stability of 3,4-Dichloro-2-fluoroaniline. The product should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent oxidation or contamination. As with all halogenated amines, appropriate personal protective equipment including gloves and eye protection should be worn during handling. We package this material in 25 kg drums, though custom packaging solutions are available to suit specific logistical requirements. Our global shipping network ensures timely delivery while complying with all international hazardous material transport regulations.