Intermediates

3,4-Difluoro-5-Nitrobenzonitrile

  • CAS No.1119454-07-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3,4-Difluoro-5-Nitrobenzonitrile for advanced organic synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

3,4-Difluoro-5-Nitrobenzonitrile is a highly specialized fluorinated aromatic intermediate designed for complex organic synthesis applications. As a critical building block in modern medicinal chemistry, this compound features a unique substitution pattern that enhances reactivity and stability during downstream processing. The presence of both fluorine atoms and a nitro group on the benzonitrile core provides versatile handles for nucleophilic aromatic substitution and reduction reactions.

Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for pharmaceutical research and development teams. The compound is rigorously tested to meet international standards, supporting the synthesis of advanced therapeutic agents and agrochemical formulations. We understand the critical nature of supply chain reliability in the chemical industry and maintain robust inventory levels to support your production schedules.

Technical Specifications

ParameterValue
CAS Number1119454-07-7
Molecular FormulaC7H2F2N2O2
Molecular Weight184.100 g/mol
AppearanceYellow powder
Assay≥95.0%
Density1.5±0.1 g/cm3
Boiling Point276.6±40.0 °C at 760 mmHg
Flash Point121.1±27.3 °C
Refractive Index1.529

Industrial Applications

This fluorinated nitrile derivative serves as a pivotal intermediate in the construction of biologically active molecules. Its primary utility lies in the pharmaceutical sector, where fluorine incorporation is known to improve metabolic stability and bioavailability of drug candidates. The nitrile functionality allows for further transformation into amines, amides, or tetrazoles, expanding its synthetic utility.

  • Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and other targeted therapies.
  • Agrochemical Development: Serves as a precursor for novel herbicides and pesticides.
  • Material Science: Applicable in the creation of specialized polymers and liquid crystals.
  • Research and Development: Essential for method development in organic chemistry laboratories.

Quality Assurance and Storage

We adhere to strict quality control protocols to ensure every batch meets the specified assay requirements. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. Proper storage is essential to maintain product integrity. We recommend storing the material in a cool, ventilated place away from direct sunlight and moisture. Packaging is available in 25 kg drums, with customization options to suit specific logistical needs.

Partnering with us provides access to technical support and a stable supply chain. Our commitment to safety and compliance ensures that all handling guidelines are met, facilitating smooth integration into your manufacturing processes. For bulk pricing and detailed technical inquiries, our sales team is ready to assist with prompt quotations and documentation.